52947-07-6

Basic information

• Product Name: methyl para-toluenesulfonate-¹³C
• Synonyms: methyl para-toluenesulfonate-¹³C
• CAS NO: 52947-07-6
• Molecular Weight: 187.221
• Mol File: 52947-07-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: methyl para-toluenesulfonate-¹³C(CAS DataBase Reference)
• NIST Chemistry Reference: methyl para-toluenesulfonate-¹³C(52947-07-6)
• EPA Substance Registry System: methyl para-toluenesulfonate-¹³C(52947-07-6)

Safety Data

• Hazardous Substances Data: 52947-07-6(Hazardous Substances Data)

Upstream product

• 14742-26-8 [¹³C]methanol 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Systematic Evaluation of 1,2-Migratory Aptitude in Alkylidene Carbenes

Alkylidene carbenes undergo rapid inter- and intramolecular reactions and rearrangements, including 1,2-migrations of β-substituents to generate alkynes. Their propensity for substituent migration exerts profound influence over the broader utility of alkylidene carbene intermediates, yet prior efforts to categorize 1,2-migratory aptitude in these elusive species have been hampered by disparate modes of carbene generation, ultrashort carbene lifetimes, mechanistic ambiguities, and the need to individually prepare a series of 13C-labeled precursors. Herein we report on the rearrangement of 13C-alkylidene carbenes generated in situ by the homologation of carbonyl compounds with [13C]-Li-TMS-diazomethane, an approach that obviates the need for isotopically labeled substrates and has expedited a systematic investigation (13C{1H} NMR, DLPNO-CCSD(T)) of migratory aptitudes in an unprecedented range of more than 30 alkylidene carbenes. Hammett analyses of the reactions of 26 differentially substituted benzophenones reveal several counterintuitive features of 1,2-migration in alkylidene carbenes that may prove of utility in the study and synthetic application of unsaturated carbenes more generally.

Purification method and preparation method of 13C methadoxetine

The invention relates to the technical field of purification of chemical drugs, in particular to a purification method and a preparation method of 13C methadoxetine. The purification method of 13C mexetine comprises the following steps: dissolving a 13C m

Trimethylsilyldiazo[13 c]methane: A versatile13 c-labelling reagent

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