5296-86-6

Basic information

• Product Name: ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate
• Synonyms: Ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate; propanoic acid, 2-[2-(4-chlorophenyl)hydrazinylidene]-, ethyl ester, (2Z)-
• CAS NO: 5296-86-6
• Molecular Formula: C₁₁H₁₃ClN₂O₂
• Molecular Weight: 240.6861
• Mol File: 5296-86-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 323.6°C at 760 mmHg
• Flash Point: 149.5°C
• Density: 1.19g/cm³
• Vapor Pressure: 0.000258mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate(5296-86-6)
• EPA Substance Registry System: ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate(5296-86-6)

Safety Data

• Hazardous Substances Data: 5296-86-6(Hazardous Substances Data)

Usage

Description

Ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate is a chemical compound with the molecular formula C11H14ClN3O2. It is a derivative of hydrazine and an ester of propanoic acid. ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate is characterized by the presence of a 4-chlorophenyl group and a hydrazono linkage, which gives it potential biological and pharmaceutical properties.

Uses

Used in Pharmaceutical Industry:
Ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate is used as an intermediate in the synthesis of various pharmaceuticals for its potential biological and pharmaceutical properties.
Used in Agrochemical Industry:
Ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate is used in the production of agrochemicals, contributing to the development of new pesticides and other agricultural products.
Used in Research and Development:
Ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate is utilized in research and development for its potential applications in medicinal chemistry and drug development, allowing scientists to explore its properties and possible uses in creating new therapeutic agents.
Safety Note:
It is important to handle ethyl (2Z)-2-[(4-chlorophenyl)hydrazono]propanoate with care and follow proper safety protocols when working with it in a laboratory setting to ensure the safety of researchers and the environment.

Upstream product

• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 17333-85-6 4-chlorophenyldiazonium salt 
• 64-17-5 ethanol 
• 5436-18-0 2-(4-chloro-phenylhydrazono)-propionic acid 
• 106-47-8 4-chloro-aniline 
• 617-35-6 2-oxo-propionic acid ethyl ester 
• 1073-69-4 N-4-chlorophenylhydrazine 
• 36966-92-4 4-Chlor-phenylnitrosamin 
• 1073-70-7 4-chlorophenylhydrazine hydrochloride 

Downstream Products

• 4792-67-0 5-chloro-indole-2-carboxylic acid ethyl ester 
• 59908-53-1 ethyl 5-chloro-1-methyl-1H-indole-2-carboxylate 
• 10517-21-2 5-chloro-1H-Indole-2-carboxylic acid 
• 17422-32-1 5-chloro-1H-indole 
• 1156510-03-0 ethyl 1-(4-chlorophenyl)-4-formyl-1H-pyrazole-3-carboxylate 
• 1224172-25-1 ethyl 1-(4-chlorophenyl)-4-(hydroxymethyl)-1H-pyrazole-3-carboxylate 
• 1224172-26-2 1-(4-chlorophenyl)-4-(hydroxymethyl)-1H-pyrazole-3-carboxylic acid 
• 1224172-22-8 tert-butyl 1-(5-(1-(4-chlorophenyl)-4-(hydroxymethyl)-1H-pyrazole-3-carboxamido)pyridin-2-yl)pyrrolidin-3-yl(methyl)carbamate 
• 1224172-24-0 tert-butyl 1-(5-(2-(4-chlorophenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)pyridin-2-yl)pyrrolidin-3-yl(methyl)carbamate 
• 1224171-03-2 2-(4-chlorophenyl)-5-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(2H)-one 
• 1224172-06-8 ethyl 1-(4-chlorophenyl)-4-((4-methoxybenzylamino)methyl)-1H-pyrazole-3-carboxylate 
• 1224172-07-9 1-(4-chlorophenyl)-4-((4-methoxybenzylamino)methyl)-1H-pyrazole-3-carboxylic acid 
• 1224172-08-0 2-(4-chlorophenyl)-5-(4-methoxybenzyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(2H)-one 
• 60557-29-1 2-(4-chloro-phenyl)-4,5-dihydro-2H-pyrrolo[3,4-c]pyrazol-6-one 

Relevant articles and documents

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Using a single drug to treat cancer with dual-targeting is an unusual approach when compared to other drug combinations. Dual-targeting agents were developed as a result of insufficient efficacy and drug resistance when single-targeting agents were used.

Substituted indole - 2 - formic acid (by machine translation)

This invention relates to a substituted indole - 2 - carboxylic acid synthesis method, is to replace the phenyl hydrazine hydrochloride or arylhydrazines as raw materials, through with pyruvic acid ethyl ester cheng zong, Fischer indole synthesis by reaction of substituted indole - 2 - carboxylic acid ethyl ester, hydrolysis to obtain the substituted - 2 - carboxylic acid. Product purity is greater than 97%, the reaction yield is 64%. Synthesis method of the invention with non-harsh conditions, the operation is simple, and environmental friendliness, it has certain economic benefits. It is a kind of raw materials are easy, simple operation, three wastes, high yield of indole - 2 - carboxylic acid synthesis method. (by machine translation)

ZnO nanoparticles as reusable heterogeneous catalyst for efficient one pot three component synthesis of imidazo-fused polyheterocycles

An efficient, simple, environmentally benign synthetic protocol is developed for synthesis of biologically and medicinally relevant pyrazole coupled imidazo[1,2-a]pyridine derivatives via three component reaction of alkyl-4-formyl-1-phenyl-1H-pyrazole-3-c