52980-20-8Relevant articles and documents
BIVALENT LECA INHIBITORS TARGETING BIOFILM FORMATION OF PSEUDOMONAS AERUGINOSA
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Page/Page column 45; 48-49; 50, (2021/05/15)
The present invention relates to divalent compounds binding to LecA. The compounds are useful to block biofilm formation of Pseudomonas aeruginosa. The invention further relates to pharmaceutical compositions comprising these compounds and to therapeutic methods and uses of these compounds, in particular to therapeutic methods and uses for the treatment of Pseudomonas aeruginosa infections in a subject. The invention also relates to imaging of infections, such as biofilms produced by Pseudomonas aeruginosa, by using these divalent compounds.
Design and characterization of novel bis-benzamide liquid crystalline materials
Iqbal, Asma,Siddiqi, Humaira Masood,Akhter, Zareen,Qaiser Fatmi, Muhammad
, p. 135 - 141 (2017/09/23)
A new homologous series of symmetric, bent-shaped bis-benzamide dimers have been prepared. Several 1,n-bis(p-aminophenoxy)alkanes (n = 3, 5, 9,10,11) were employed as spacers and p-hexyloxy tails have been synthesized and appended to the spacers by amide linking groups. Different important parameters were explored using computational analysis by semi empirical method. The experimental results were correlated with theoretical studies and relationship between molecular structure and mesogenic behavior has been established. The mesomorphic properties of the resultant dimers were characterized by differential scanning calorimetry (DSC) and polarized optical microscopy (POM) equipped with a hot stage. Change in mesomorphic properties with change of methylene spacers was observed. Enantiotropic mesogenic behavior was exhibited by D3A6, D10A6 and D11A6 and the needle like and blurred schleiren textures were observed. It was observed that increased methylene spacers chain length decreased the melting temperatures. Thermogravimetric analysis revealed the thermal stability of dimers upto 360 °C.
Synthesis and characterization of new optically active poly(amide-imide)s based on n-trimellitimido-l-amino acid and trimethylene units
Faghihi, Khalil,Shabanian, Meisam
scheme or table, p. 97 - 102 (2012/05/20)
Six new optically active poly(amide-imide)s (8a-f) were synthesized through the direct polycondensation reaction of 1,3-bis(4-aminophenoxy) propane (4) with six different derivatives of N-trimellitimido-L-amino acid (7a-f) in a medium consisting of N-meth