53054-76-5 Usage
Description
4-Pyridineethanesulfonic acid, also known as 2-(4-Pyridyl)ethanesulfonic acid, is a chemical compound derived from the sulfonation of pyridine. It is a white crystalline solid with a molecular formula of C11H15NO3S and is soluble in water. 4-Pyridineethanesulfonic acid is known for its role as a sulfonated substrate for alkanesulfonate monooxygenase, an enzyme isolated from Escherichia coli.
Uses
Used in Chemical Synthesis:
4-Pyridineethanesulfonic acid is used as a chemical intermediate for the preparation of various compounds, such as benzyldimethyltetradecyl ammonium chloride dihydrate solution. This application is significant in the synthesis of new molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Pyridineethanesulfonic acid may be utilized as a building block for the development of new drugs, particularly those targeting enzymes like alkanesulfonate monooxygenase. Its unique chemical structure allows for the creation of novel compounds with potential therapeutic properties.
Used in Research and Development:
4-Pyridineethanesulfonic acid is also used in research and development settings, where it can serve as a model compound for studying the interactions between enzymes and their substrates. This knowledge can be applied to better understand enzyme mechanisms and develop targeted therapies for various diseases.
Used in Analytical Chemistry:
Due to its solubility and stability, 4-Pyridineethanesulfonic acid can be employed as a buffer component in analytical chemistry. It can help maintain a constant pH during experiments, ensuring accurate and reliable results.
Check Digit Verification of cas no
The CAS Registry Mumber 53054-76-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,0,5 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 53054-76:
(7*5)+(6*3)+(5*0)+(4*5)+(3*4)+(2*7)+(1*6)=105
105 % 10 = 5
So 53054-76-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H9NO3S/c9-12(10,11)6-3-7-1-4-8-5-2-7/h1-2,4-5H,3,6H2,(H,9,10,11)
53054-76-5Relevant articles and documents
COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY
-
Page/Page column 144, (2019/09/18)
This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt and/or hydrate and/or prodrug of the compound) that modulate (e.g., agonize) the apelin receptor (also referred to herein as the APJ receptor; gene symbol "APLNR"). This disclosure also features compositions containing the same as well as other methods of using and making the same. The chemical entities are useful, e.g., for treating a subject (e.g., a human) having a disease, disorder, or condition in which a decrease in APJ receptor activity (e.g., repressed or impaired APJ receptor signaling; e.g., repressed or impaired apelin-APJ receptor signaling) or downregulation of endogenous apelin contributes to the pathology and/or symptoms and/or progression of the disease, disorder, or condition. Non-limiting examples of such diseases, disorders, or conditions include: (i) cardiovascular disease; (ii) metabolic disorders; (iii) diseases, disorders, and conditions associated with vascular pathology; and (iv) organ failure; (v) diseases, disorders, and conditions associated with infections (e.g., microbial infections); and (vi) diseases, disorders, or conditions that are sequela or comorbid with any of the foregoing or any disclosed herein. More particular non-limiting examples of such diseases, disorders, or conditions include pulmonary hypertension (e.g., PAH); heart failure; type II diabetes; renal failure; sepsis; and systemic hypertension.