5308-63-4

Basic information

• Product Name: 1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE
• Synonyms: 2-ACETYL-5-METHYLPYRIDINE;1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE;Ethanone, 1-(5-methyl-2-pyridinyl)-;1-(5-methyl-2-pyridinyl)ethanone(SALTDATA: HCl);1-(5-Methyl-2-pyridinyl)-Ethanone
• CAS NO: 5308-63-4
• Molecular Formula: C₈H₉NO
• Molecular Weight: 135.16
• Product Categories: Pyridines
• Mol File: 5308-63-4.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 217.1°C at 760 mmHg
• Flash Point: 89.8°C
• Appearance: /
• Density: 1.036g/cm³
• Vapor Pressure: 0.135mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 3.29±0.10(Predicted)
• CAS DataBase Reference: 1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE(5308-63-4)
• EPA Substance Registry System: 1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE(5308-63-4)

Safety Data

• Hazardous Substances Data: 5308-63-4(Hazardous Substances Data)

Usage

General Description

1-(5-Methyl-pyridin-2-yl)-ethanone, also known as 5-Methyl-2-pyridyl methyl ketone, is a chemical compound with the molecular formula C8H9NO. It is a yellow to brown liquid with a pungent odor. 1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals due to its ability to react with a variety of reagents to form different derivatives. It is also used in the production of fragrances and flavoring compounds. However, 1-(5-Methyl-pyridin-2-yl)-ethanone is considered to be a hazardous chemical due to its potential for causing irritation to the skin, eyes, and respiratory system, and should be handled and stored with caution.

InChI:InChI=1/C8H9NO/c1-6-4-3-5-9-8(6)7(2)10/h3-5H,1-2H3

Upstream product

• 85279-27-2 1-(6-methyl-2-piperidyl)ethan-1-ol 
• 74-88-4 methyl iodide 
• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 127-19-5 N,N-dimethyl acetamide 
• 1122-72-1 6-methyl-2-pyridinecarboxaldehyde 
• 71777-66-7 (+/-)-1-[2-(6-methylpyridyl)]ethanol 
• 3510-66-5 2-Bromo-5-methylpyridine 
• 1620-77-5 5-methylpicolinonitrile 
• 75-16-1 methylmagnesium bromide 
• 18113-81-0 2-ethyl-5-methylpyridine 

Downstream Products

• 183187-82-8 5,5’’-bis(bromomethyl)-2,2’:6’,2’’-terpyridine 
• 379226-93-4 1-(5-Methyl-2-pyridyl)-1-ethanone-1-(1-methyl-1H-benzo[d]imidazol-2-yl)-hydrazone 
• 1429939-70-7 C₂₁H₁₉F₄N₅O 
• 1429939-77-4 C₂₁H₂₀F₃N₅O 
• 1429939-91-2 C₁₀H₉F₂NO₂ 

Relevant articles and documents

A highly rigid ditopic conjugate with orthogonal coordination axes and its zinc(II) and copper(II) complexes

A highly rigid ditopic ligand has been prepared which consists of a terpy fragment connected in the back to a phen nucleus via a 1,4-phenylene linker. The chemical structure of the presently reported ligand is such that the coordination axes of the two ch

Quantitative Sensitization Efficiencies in NIR-Emissive Homoleptic Ln(III) Complexes Using 2-(5-Methylpyridin-2-yl)-8-hydroxyquinoline

A series of isostructural lanthanide complexes [Ln(MPQ)3] (Ln = Nd, Gd, Er, Yb, Lu) using a monoanionic tridentate methylpyridyl-substituted 8-hydroxyquinoline ligand (MPHQ = 2-(5-methylpyridin-2-yl)-8-hydroxyquinoline) have been prepared and c

A mesoporous NNN-pincer-based metal-organic framework scaffold for the preparation of noble-metal-free catalysts

Through topology-guided synthesis, a Zr-based mesoporous MOF was successfully constructed, adopting a β-cristobalite-type structure. The MOF is embedded with well-arranged terpyridine coordination sites for facile post-synthetic metalation, and can be effectively used as a general scaffold for the preparation of noble-metal-free catalysts. For instance, the scaffolded metal@MOF material exhibits highly efficient catalytic activity for alkene epoxidation and arene borylation.

N ortho acyl substituted nitrogen-containing heterocyclic compound and process for preparing aminal iron (II) complexes thereof

Provided are a process for preparing an N ortho acyl substituted nitrogen-containing heterocyclic compound and an aminal iron (II) complex thereof, and the use of the complexes obtained by the process in an olefin oligomerization catalyst. The N ortho acyl substituted nitrogen-containing heterocyclic compound in the present invention is for example 2-acyl-1,10-phenanthroline or 2,6-diacetyl pyridine as shown in formula b, and the N ortho acyl substituted nitrogen-containing heterocyclic compound in the present invention is produced by a reaction of a precursor thereof in a substituted or unsubstituted nitrobenzene. Preferably the precursor shown in formula I in the present invention is produced by 1,10-phenanthroline reacting with trialkyl aluminum, or a halogenoalkyl aluminum RnAIXm, or a substituted or unsubstituted benzyl lithium Ph′CH2Li, followed by hydrolysis. The preparation method provided in the present invention has a few synthetic steps, an easy process, a low toxic effect, and reduces the preparation costs of the catalyst, and has a promising outlook in the industrial application.