53090-86-1

Basic information

• Product Name: (6R)-3-[[(1-Methyl-1H-tetrazole-5-yl)thio]methyl]-7α-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid diphenylmethyl ester
• Synonyms: (6R)-3-[[(1-Methyl-1H-tetrazole-5-yl)thio]methyl]-7α-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid diphenylmethyl ester;(6R,7R)-7-Amino-3-[(1-methyl-1H-tetrazol-5-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester;(6R,7R)-Benzhydryl 7-amino-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• CAS NO: 53090-86-1
• Molecular Formula: C₂₃H₂₂N₆O₃S₂
• Molecular Weight: 494.59
• Mol File: 53090-86-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (6R)-3-[[(1-Methyl-1H-tetrazole-5-yl)thio]methyl]-7α-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid diphenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (6R)-3-[[(1-Methyl-1H-tetrazole-5-yl)thio]methyl]-7α-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid diphenylmethyl ester(53090-86-1)
• EPA Substance Registry System: (6R)-3-[[(1-Methyl-1H-tetrazole-5-yl)thio]methyl]-7α-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid diphenylmethyl ester(53090-86-1)

Safety Data

• Hazardous Substances Data: 53090-86-1(Hazardous Substances Data)

Usage

Description

(6R)-3-[[(1-Methyl-1H-tetrazole-5-yl)thio]methyl]-7α-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid diphenylmethyl ester is a complex organic compound characterized by its unique structure, which includes a 1-methyl-1H-tetrazole-5-yl group, a thioether linkage, an amino acid backbone, and a diphenylmethyl ester functionality. Its intricate molecular architecture suggests potential bioactive properties and pharmaceutical applications, although further research and experimentation are required to fully comprehend its capabilities and effects.

Uses

Used in Pharmaceutical Industry:
(6R)-3-[[(1-Methyl-1H-tetrazole-5-yl)thio]methyl]-7α-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid diphenylmethyl ester is used as a potential pharmaceutical agent for its unique molecular structure, which may offer novel bioactive properties and therapeutic applications.
Used in Chemical Research:
In the field of chemical research, this compound serves as a subject for further investigation and experimentation. Its complex structure may provide insights into new reaction mechanisms, synthetic pathways, and potential applications in various chemical processes.
Used in Material Science:
(6R)-3-[[(1-Methyl-1H-tetrazole-5-yl)thio]methyl]-7α-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid diphenylmethyl ester's unique structural features may also find applications in material science, where it could be utilized in the development of new materials with specific properties, such as improved stability, reactivity, or selectivity in various chemical reactions.

InChI:InChI=1/C23H22N6O3S2/c1-28-23(25-26-27-28)34-13-16-12-33-21-17(24)20(30)29(21)18(16)22(31)32-19(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,17,19,21H,12-13,24H2,1H3/t17-,21-/m1/s1

Upstream product

• 24209-38-9 (6R,7R)-7-amino-3-[(1H-1-methyltetrazol-5-yl)thio]methylceph-3-em-4-carboxylic acid 
• 908093-98-1 diazodiphenylmethane 

Downstream Products

• 120155-60-4 7-((Z)-3-Chloro-2-thiazol-4-yl-acryloylamino)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 64278-67-7 (R)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-7-p-tolylsulfanylimino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 64278-70-2 (R)-7-methylsulfanylimino-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 62279-88-3 (6R)-7t-[(R)-2-(4-methoxy-benzyloxycarbonylamino)-2-thiophen-2-yl-acetylamino]-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 62859-90-9 (6R)-7t-[(S)-2-(4-methoxy-benzyloxycarbonylamino)-2-thiophen-2-yl-acetylamino]-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 56023-19-9 (6R)-7t-(3,5-di-tert-butyl-4-hydroxy-benzylideneamino)-7c-methoxy-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 58844-13-6 (6R)-7t-(3,5-di-tert-butyl-4-hydroxy-benzylideneamino)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 64278-67-7 (6R)-7-<<(4-methylphenyl)thio>imino>-3-<<(1-methyl-1H-tetrazol-5-yl)thio>methyl>-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester 
• 64278-66-6 (6R,7R)-3-(1-Methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-7-p-tolylsulfanylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 64278-68-8 C₃₇H₃₄N₆O₃S₄ 
• 64278-70-2 (6R)-3-<<(1-methyl-1H-tetrazol-5-yl)thio>methyl>-7-(methylthioimino)-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester 
• 81482-44-2 C₂₅H₂₀F₆N₆O₇S₄ 
• 86862-91-1 (6R,7R)-7-{2-(4-Methoxy-benzyloxycarbonyl)-2-[4-(4-methoxy-benzyloxy)-phenyl]-acetylamino}-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 86862-85-3 (6R,7R)-7-[2-(4-Benzyloxycarbonyloxy-phenyl)-acetylamino]-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 

Relevant articles and documents

Quaternary Heterocyclylamino β-Lactams: A Generic Alternative to the Classical Acylamino Side Chain

6β-penam-3-carboxylates and 7β-ceph-3-em-4-carboxylates have been found to be interesting new classes of antibacterial β-lactams, readily available by SN2 Ar coupling of fluoro-substituted quaternized pyridines and appropriate amino lactam carboxylic acids.Compared to penicillin G, the penam 12c exhibited a spectrum extended to Gram-negative species, such as Escherichia, Shigella, Klebsiella and Enterobacter, offset by a loss of potency against Gram-positive spacies.Excluding Pseudomonas, many examples of the cephems showed excellent activity against the above Gram-negative organisms, and in some cases, such as 15i, the spectrum included good performance against the staphylococci and streptococci.With Serratia and many Proteus species, there was an adverse inoculum and medium effect which was not observed in the good Gram-positive reach of the cephem series.

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