53165-18-7

Basic information

• Product Name: Acetamide, N-(4-chloro-2-formylphenyl)-
• CAS NO: 53165-18-7
• Molecular Formula: C9H8ClNO2
• Molecular Weight: 197.621
• Mol File: 53165-18-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(4-chloro-2-formylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(4-chloro-2-formylphenyl)-(53165-18-7)
• EPA Substance Registry System: Acetamide, N-(4-chloro-2-formylphenyl)-(53165-18-7)

Safety Data

• Hazardous Substances Data: 53165-18-7(Hazardous Substances Data)

Upstream product

• 63069-48-7 p-chloro-o-iodoaniline 
• 13493-47-5 N-(2-formylphenyl)acetamide 

Downstream Products

• 1158909-87-5 N-(4-chloro-2-[2-(2,4-dichloro-phenoxy)-phenylamino]-methyl-phenyl)-acetamide 
• 1810-67-9 6-chloroquinolin-2(1H)-oney 
• 1003024-70-1 methyl 3-(2-acetamido-5-chlorophenyl)-3-hydroxy-2-methylenepropanoate 
• 98083-43-3 1-Acetyl-5-chlorindazol 

Relevant articles and documents

A general synthesis of novel quinoline-based isoindolin-1-one derivatives

A simple and general one-pot protocol for the synthesis of a series quinoline-based isoindolin-l-ones, namely 7-chloro-2-substituted-2,3-dihydro- 1H-pyrrolo[3,4-b]quinolin-1-ones (5a-p) is described, involving a cascade Williamson-type condensation reacti

COMPOUND

There is provided a compound having Formula (I), wherein each of R1, R2, R3, R4, R5, R6, R7, R8 and R9 are independently selected from (a) H, (b) R13, -OC(R13)3, -OCH(R13)2, -OCH2R13, -C(R13)3, -CH(R13)2, or -CH2R13 wherein R13 is a halogen; (c) -CN; (d) optionally substituted alkyl, (e) optionally substituted heteroalkyl; (f) optionally substituted aryl; (g) optionally substituted heteroaryl; (h) optionally substituted arylalkyl; (i) optionally substituted heteroarylalkyl; (j) hydroxy; (k) alkoxy; (I) aryloxy; (m) -SO2-alkyl; and (n) -N(R14)C(O)R15, wherein R14 and R15 are independently selected from H and hydrocarbyl, wherein the optional substituents of (d) (e) (T) (h) and (i) are selected from the group consisting of: C1-6 alkyl, halo, cyano, nitro, haloalkyl, hydroxy, C1-6 alkoxy, carboxy, carboxyalkyl, carboxamide, mercapto, amino, alkylamino, dialkylamino, sulfonyl, sulfonamido, aryl and heteroaryl; wherein n and p are independently selected from 0 and 1; X is an optional group selected from O, S, S=O, S(=O)2, C=O, S(=O)2NR16, C=ONR17, NR18, in which R16, R17, and R18 are independently selected from H and hydrocarbyl, R10 is selected from H and hydrocarbyl, R11 is selected from CR19R20 and C=O, in which R19 and R20 are independently selected from H and hydrocarbyl, R12 is selected from a substituted five or six membered carbon rings optionally containing one or more hetero atoms selected from N, S, and O and optionally having fused thereto a further ring, and wherein the one or more substituents are selected from hydrocarbyl groups.