53202-58-7Relevant articles and documents
Solvent-induced selectivity of Williamson etherification in the pursuit of amides resistant against oxidative degradation
Clark, John A.,Derr, James B.,Espinoza, Eli M.,Morales, Maryann,Vadhin, Sandra,Vullev, Valentine I.
, p. 24419 - 24424 (2020/07/13)
This article reports two discoveries. (1) 2-Methoxyethanol induces unprecedented selectivity for etherification of 5-hydroxy-2-nitrobenzic acids without forming undesired esters. (2) Such compounds are precursors for amides showing unusual robustness agai
BENZODIAZEPINE AND BENZOPIPERAZINE ANALOG INHIBITORS OF HISTONE DEACETYLASE
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Page/Page column 94, (2010/11/26)
This invention relates to compounds for the inhibition of histone deacetylase More particularly, the invention provides for compounds of formula (I): wherein A, B, D, E, X1, X2, X3, X4 and n are as defined in the specification A method of inhibiting histone deacetylase in a cell, the method comprising contacting the cell with a compound of formula (I), in an amount sufficient to inhibit histone deacetylase, is also disclosed.
Synthesis and antinephritic activities of quinoline-3-carboxamides and related compounds
Tsuji, Kiyoshi,Spears, Glen W.,Nakamura, Katsuya,Tojo, Takashi,Seki, Nobuo,Sugiyama, Aiko,Matsuo, Masaaki
, p. 85 - 88 (2007/10/03)
A series of linomide-related quinoline-3-carboxamides and their analogues was prepared and evaluated for antinephritic activities. The 6-MeS derivative 7a was highly effective in two nephritis models, namely chronic graft-versus-host disease and autoimmune MRL/l mice.
