53341-66-5

Basic information

• Product Name: ethyl 3-oxo-3-(phenylamino)propanoate
• Synonyms: Ethyl 3-anilino-3-oxopropanoate; Propanoic acid, 3-oxo-3-(phenylamino)-, ethyl ester
• CAS NO: 53341-66-5
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.2258
• Mol File: 53341-66-5.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 385.7°C at 760 mmHg
• Flash Point: 187.1°C
• Density: 1.18g/cm³
• Vapor Pressure: 3.74E-06mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: ethyl 3-oxo-3-(phenylamino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-oxo-3-(phenylamino)propanoate(53341-66-5)
• EPA Substance Registry System: ethyl 3-oxo-3-(phenylamino)propanoate(53341-66-5)

Safety Data

• Hazardous Substances Data: 53341-66-5(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 36239-09-5 ethyl chlorocarbonylacetate 
• 71-43-2 benzene 
• 105-53-3 diethyl malonate 
• 4504-12-5 ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxaldehyde 
• 102626-05-1 ethyl 3-amino-2-phenylaminocarbonyl-2-butenoate 
• 1010117-23-3 diethyl 2-nitro-3-oxopentanedioate 
• 623-73-4 diazoacetic acid ethyl ester 
• 201230-82-2 carbon monoxide 
• 64-17-5 ethanol 
• 261639-91-2 5-[(hydroxy)(phenylamino)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 623-48-3 ethyl iodoacetae 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 15580-32-2 malonanilic acid 
• 102877-88-3 Ethyl (1-phenyl-1,2,3,4-tetrazol-5-yl)acetate 
• 15775-57-2 N-methyl-N'-phenylmalonamide 
• 13663-95-1 2-Anilinothiocarbonyl-malonsaeure-ethylester-anilid 
• 3122-27-8 ethyl 3,3-bis(ethylthio)-2-(phenylcarbamoyl)acrylate 
• 15601-64-6 3-hydrazineyl-3-oxo-N-phenylpropanamide 
• 128174-87-8 ethyl 2,2-bis(chlorothio)-3-oxo-3-(phenylamino)propanoate 
• 621-10-3 N,N'-diphenylmalonamide 
• 105-53-3 diethyl malonate 
• 14655-26-6 2-oxo-1,2-dihydro-quinoline-3-carboxylic acid anilide 
• 75544-71-7 3-Anilino-2-(phenylcarbamoyl)propensaeure-ethylester 
• 111508-36-2 2-ethoxy-2-phenylaminomalonic acid monoethyl ester N-phenylcarboxamide 
• 55244-09-2 2-hydroxymalonanilic acid ethyl ester 
• 93847-24-6 2-phenyliminomalonic acid monoethyl ester N-phenylcarboxamide 

Relevant articles and documents

THIENOPYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Since a thienopyridine derivative compound represented by chemical formula 1 or a pharmaceutically acceptable salt thereof of the present invention has an excellent effect of inhibiting protein kinase activity, a pharmaceutical composition comprising the same can be usefully used for preventing or treating diseases related to protein kinase activity.COPYRIGHT KIPO 2020

AlCl 3 -Mediated Synthesis of 4-Aryl-2-quinolone-3-carboxylates

4-Aryl-2-quinolones are important skeletons from both chemical and medicinal viewpoints. We herein report the development of an efficient synthetic method for 3-substituted 4-aryl-2-quinolones. The key reaction in this process involves an AlCl 3/sub

QUINOLINE DERIVATIVE

This compound represented by general formula (I) and having a quinoline skeleton has a strong Axl inhibitory activity. Consequently, this compound can be a therapeutic agent for Axl-related diseases, for example, cancers such as acute myeloid leukemia, chronic myeloid leukemia, melanoma, breast cancer, pancreatic cancer and glioma, kidney diseases, immune system diseases and cardiovascular diseases.