53346-62-6

Basic information

• Product Name: 3(2H)-Pyridazinone, 6-(4-bromophenyl)-, hydrazone
• Synonyms: 3(2H)-Pyridazinone,6-(4-bromophenyl)-,hydrazone;3-(4-bromophenyl)-6-hydrazinopyridazine
• CAS NO: 53346-62-6
• Molecular Formula: C10H9BrN4
• Molecular Weight: 265.11
• Mol File: 53346-62-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3(2H)-Pyridazinone, 6-(4-bromophenyl)-, hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Pyridazinone, 6-(4-bromophenyl)-, hydrazone(53346-62-6)
• EPA Substance Registry System: 3(2H)-Pyridazinone, 6-(4-bromophenyl)-, hydrazone(53346-62-6)

Safety Data

• Hazardous Substances Data: 53346-62-6(Hazardous Substances Data)

Upstream product

• 6340-79-0 4-oxo-4-(4-bromophenyl)butanoic acid 
• 36725-37-8 6-(4-bromophenyl)-4,5-dihydropyridazin-3(2H)-one 
• 108-86-1 bromobenzene 
• 316174-47-7 6-(p-bromophenyl)-4-(4-anitpyrinyl)-4,5-dihydropyridazin-3(2H)-one 
• 316174-45-5 4-(p-bromophenyl)-4-oxo-2-(4-antipyrinyl)butanoic acid 
• 20972-38-7 (E)-4-(4-bromophenyl)-4-oxobut-2-enoic acid 
• 66548-50-3 3-(p-bromophenyl)-6-chloropyridazine 

Downstream Products

• 956150-95-1 3-phenyl-6-(4'-bromophenyl)-1,2,4-triazolo[4,3-b]pyridazine 
• 1268133-96-5 3-(4'-tolyl)-6-(4'-bromophenyl)-1,2,4-triazolo[4,3-b]pyridazine 
• 66129-25-7 6-(4-bromophenyl)-3-methyl[1,2,4]triazolo[4,3-b]pyridazine 
• 1236309-69-5 2-[6-(4-bromophenyl)pyridazin-3-yl]-5-methyl-2,4-dihydro-3H-pyrazol-3-one 

Relevant articles and documents

Synthesis, antituberculostatic, antifungal and antibacterial activities of 3-substituted phenyl-6-substituted phenyl-1,2,4-triazolo[4,3-b]pyridazines

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Synthesis and Reactions of 4-(p-Bromophenyl)-4-oxo-2-(4-antipyrinyl)-butanoic Acid and Some Unexpected Products

Reaction of antipyrin with 4-oxo-4-(p-bromophenyl)-2-butenoic acid gave the butanoic acid derivative 3. Reaction of 3 with o-phenylenediamine in presence of hydrochloric acid gave the unexpected condensation with dearylation product 4. Reaction of 3 with hydrazines gave the pyridazinone derivatives 5 and 7. Reaction of 5 with phosphoryl chloride gave the unexpected product 6-(p-bromophenyl)-3-chloropyridazine 8. The reactions of 5 with formaldehyde-piperidine, ethyl chloroacetate, acetyl chloride, acrylonitrile and chloroacetic acid gave the N-substituted products. The behaviour of compound 8 toward each of hydrazine hydrate, sodium azide, anthranilic acid, acid hydrazides and sulfa derivatives was also studied. Mechanisms for the reactions have been proposed.