53391-62-1

Basic information

• Product Name: Ethanone, 2-chloro-1-(1H-pyrrol-2-yl)- (9CI)
• Synonyms: Ethanone, 2-chloro-1-(1H-pyrrol-2-yl)- (9CI);Ketone, chloromethyl pyrrol-2-yl;2-chloro-1-(1H-pyrrol-2-yl)ethan-1-one
• CAS NO: 53391-62-1
• Molecular Formula: C₆H₆ClNO
• Molecular Weight: 143.57094
• Product Categories: ACETYLHALIDE
• Mol File: 53391-62-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 274.9°Cat760mmHg
• Flash Point: 120.1°C
• Appearance: /
• Density: 1.297g/cm³
• Vapor Pressure: 0.00525mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: Ethanone, 2-chloro-1-(1H-pyrrol-2-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-1-(1H-pyrrol-2-yl)- (9CI)(53391-62-1)
• EPA Substance Registry System: Ethanone, 2-chloro-1-(1H-pyrrol-2-yl)- (9CI)(53391-62-1)

Safety Data

• Hazardous Substances Data: 53391-62-1(Hazardous Substances Data)

Usage

General Description

Ethanone, 2-chloro-1-(1H-pyrrol-2-yl)- (9CI), also known as 2-chloro-N-pyrrol-2-yl-acetamide, is an organic compound with the molecular formula C6H6ClNO. It is a chlorinated derivative of pyrrole, containing a carbonyl group connected to a pyrrole ring. Ethanone, 2-chloro-1-(1H-pyrrol-2-yl)- (9CI) is commonly used in pharmaceutical and research applications due to its potential biological and pharmacological properties. It has been studied for its potential as an anticonvulsant and has shown promising results in animal models. Additionally, it has been investigated for its potential as a building block in the synthesis of more complex organic compounds. Overall, Ethanone, 2-chloro-1-(1H-pyrrol-2-yl)- (9CI) is a versatile chemical with potential applications in various fields.

InChI:InChI=1/C6H6ClNO/c7-4-6(9)5-2-1-3-8-5/h1-3,8H,4H2

Upstream product

• 109-97-7 pyrrole 
• 107-14-2 chloroacetonitrile 
• 2675-89-0 2-chloro-N,N-dimethylacetamide 
• 1072-83-9 2-Acetylpyrrole 
• 79-04-9 chloroacetyl chloride 
• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 

Downstream Products

• 857419-85-3 1,5-di-pyrrol-2-yl-3-thia-pentane-1,5-dione 
• 55984-20-8 2-Iodacetyl-pyrrol 
• 76007-20-0 2-N-methylanilinoacetylpyrrole 
• 76584-28-6 1-(1H-Pyrrol-2-yl)-2-(triphenyl-λ⁵-phosphanylidene)-ethanone 
• 861591-86-8 2-amino-1-pyrrol-2-yl-ethanone 
• 1072-83-9 2-Acetylpyrrole 
• 1147836-19-8 2-(2-iodophenoxy)-1-(1H-pyrrol-2-yl)ethanone 
• 1417565-80-0 C₁₃H₁₂INO₂ 
• 1417565-81-1 C₁₄H₁₄INO₂ 
• 1417565-82-2 C₁₅H₁₆INO₂ 
• 1417565-83-3 C₁₆H₁₈INO₂ 
• 1417565-95-7 2-(benzyloxy)benzo[b]pyrrolo[1,2-d][1,4]oxazepin-7(6H)-one 
• 1417565-84-4 C₁₉H₁₆INO₃ 
• 1417565-85-5 C₁₄H₁₃IN₂O₃ 

Relevant articles and documents

Chemoselective Reduction of Trichloromethyl Compounds to gem-Dichloromethyl Groups Following Appel's Reaction Protocol

A simple and easy reduction of trichloroacetyl compounds following the modification of Appel's reaction protocol, using triphenylphosphine and methanol, afforded the corresponding dichloroacetyl compounds, with the exception of trichloroacetylmorpholine,

Enantioselective synthesis of heteroaromatic epoxyketones under phase-transfer catalysis using D-glucose- and D-mannose-based crown ethers

Heteroaromatic epoxyketones have been synthesized in an asymmetric Darzens condensation of 2-chloroacetylfuran or 2- and 3-chloroacetylthiophene with aromatic aldehydes and in the enantioselective epoxidation of α,β-enones with an N-methylpyrrole unit, in

Selective α-Chlorination of Acetylpyrroles

Reaction of acetylpyrroles with benzyltrimethylammonium dichloroiodate in tetrahydrofuran solution leads to the corresponding α-chloro derivatives with high selectivity and good yields.