53440-12-3 Usage
Description
1,2,3,4-Tetrahydro-2-naphthoic Acid is an organic compound with the molecular formula C11H12O2. It is a white crystalline solid and is a derivative of naphthoic acid, which is a type of dicarboxylic acid. 1,2,3,4-TETRAHYDRO-2-NAPHTHOIC ACID is characterized by its unique chemical structure, which consists of a naphthalene ring with four hydrogen atoms attached to the second carbon, and a carboxylic acid group attached to the first carbon.
Uses
Used in Chemical Synthesis:
1,2,3,4-Tetrahydro-2-naphthoic Acid is used as a reagent in the organic synthesis of various compounds. Its unique chemical structure allows it to participate in a range of reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
1,2,3,4-Tetrahydro-2-naphthoic Acid is used in the synthesis of N-acyl-5-methyl-3(2H)-isoxazolone derivatives, which have shown high potential as fungicides. These derivatives can be used to develop new antifungal agents to combat fungal infections, which are a significant concern in both human medicine and agriculture.
Used in Agricultural Industry:
In the agricultural industry, 1,2,3,4-Tetrahydro-2-naphthoic Acid is used as a starting material for the development of new fungicides. These fungicides can be employed to protect crops from fungal diseases, which can cause significant losses in yield and quality. By using this compound in the development of new fungicides, it can contribute to the improvement of crop protection strategies and help ensure food security.
Check Digit Verification of cas no
The CAS Registry Mumber 53440-12-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,4,4 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 53440-12:
(7*5)+(6*3)+(5*4)+(4*4)+(3*0)+(2*1)+(1*2)=93
93 % 10 = 3
So 53440-12-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O2/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-4,10H,5-7H2,(H,12,13)/t10-/m1/s1
53440-12-3Relevant articles and documents
Photoredox Activation of Formate Salts: Hydrocarboxylation of Alkenes via Carboxyl Group Transfer
Huang, Yan,Hou, Jing,Zhan, Le-Wu,Zhang, Qian,Tang, Wan-Ying,Li, Bin-Dong
, p. 15004 - 15012 (2021/12/14)
A photoredox activation mode of formate salts for carboxylation was developed. Using a formate salt as the reductant, carbonyl source, and hydrogen atom transfer reagent, a wide range of alkenes can be converted into acid products via a carboxyl group tra
Rapid Construction of Tetralin, Chromane, and Indane Motifs via Cyclative C-H/C-H Coupling: Four-Step Total Synthesis of (±)-Russujaponol F
Zhuang, Zhe,Herron, Alastair N.,Liu, Shuang,Yu, Jin-Quan
, p. 687 - 692 (2021/01/25)
The development of practical C-H/C-H coupling reactions remains a challenging yet appealing synthetic venture because it circumvents the need to prefunctionalize both coupling partners for the generation of C-C bonds. Herein we report a cyclative C(sp3)-H/C(sp2)-H coupling reaction of free aliphatic acids enabled by a cyclopentane-based mono-N-protected β-amino acid ligand. This reaction uses inexpensive sodium percarbonate (Na2CO3·1.5H2O2) as the sole oxidant and generates water as the only byproduct. A range of biologically important scaffolds, including tetralins, chromanes, and indanes, can be easily prepared by this protocol. Finally, the synthetic application of this methodology is demonstrated by the concise total synthesis of (±)-russujaponol F in a four-step sequence starting from readily available phenylacetic acid and pivalic acid through sequential functionalizations of four C-H bonds.
5-AMINO-4-CARBAMOYL-PYRAZOLE COMPOUNDS AS SELECTIVE AND IRREVERSIBLE T790M OVER WT-EGFR KINASE INHIBITORS AND USE THEREOF????
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Paragraph 0178, (2016/03/13)
Disclosed are compounds of Formula (I), pharmaceutical compositions comprising the same, processes for the preparation thereof, and the use thereof.
