5348-51-6 Usage
Description
2-Hydroxy-4-methylpyrimidine hydrochloride, with the CAS number 5348-51-6, is a chemical compound that is characterized by its yellow to orange powder form. It is primarily recognized for its utility in the realm of organic synthesis, where it serves as a valuable building block for the creation of more complex molecules.
Uses
Used in Organic Synthesis:
2-Hydroxy-4-methylpyrimidine hydrochloride is used as a synthetic building block for the development of various organic compounds. Its unique chemical structure allows it to be a versatile component in the synthesis of a wide range of molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Hydroxy-4-methylpyrimidine hydrochloride is utilized as an intermediate in the synthesis of therapeutic agents. Its incorporation into the molecular structure of drugs can contribute to the development of novel medications with improved efficacy and selectivity.
Used in Agrochemical Industry:
2-Hydroxy-4-methylpyrimidine hydrochloride also finds application in the agrochemical industry, where it is employed in the synthesis of active ingredients for pesticides and other crop protection products. Its use in this context can lead to the development of more effective and environmentally friendly solutions for agricultural challenges.
Used in Specialty Chemicals:
Beyond its applications in the pharmaceutical and agrochemical industries, 2-Hydroxy-4-methylpyrimidine hydrochloride is also used in the synthesis of specialty chemicals. These can include dyes, additives, and other compounds that serve specific purposes in various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5348-51-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,4 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5348-51:
(6*5)+(5*3)+(4*4)+(3*8)+(2*5)+(1*1)=96
96 % 10 = 6
So 5348-51-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2O.ClH/c1-4-2-3-6-5(8)7-4;/h2-3H,1H3,(H,6,7,8);1H
5348-51-6Relevant articles and documents
Six pyrimidonium salts: determination of their crystal structures and studies of their prototropic behaviour in solution
Lee, Thomas W. S.,Rettig, Steven J.,Stewart, Ross,Trotter, James
, p. 1194 - 1202 (2007/10/02)
Six methyl-substituted 2-pyrimidonium chloride salts have been prepared and the rates of hydrogen exchange of their reactive methyl groups (at the 4- and 6- positions) have been determined in DCl/D2O solution.Adjacent methyl groups, whether on nitrogen or carbon, activate the exchanging centres, whereas more distant methyl groups have a deactivating effect.The molecular geometry of the salts has been determined by X-ray crystallography with the view to determining whether the presence of strain in the pyrimidonium ring can account for the activating effect of adjacent methyl.The most reactive compound, the 1,5,6-trimethylpyrimidonium chlride, has a geometry that is consistent with high reactivity, viz. a non-planar ring and short H...H intermethyl distance.However, the 1,4,5,6-tetramethyl compound, which also is nonplanar and has an extremely short 5-6 intermethyl distance (1.99 Angsroem), is not highly reactive; that is, the heightened strain is unable to overcome the deactivating inductive effect of the additional methyl group.We conclude that deviations from ring planarity and short intermethyl distances are insufficient to account for the activation produced by adjacent methyl though they appear to be contributing factors to this effect.
