535952-65-9

Basic information

• Product Name: (S)-N-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-N'-[2-(9-fluorenylmethoxycarbonyl)amino-4-phenylbutylcarbonyl]methylisothiourea
• Synonyms: (S)-N-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-N'-[2-(9-fluorenylmethoxycarbonyl)amino-4-phenylbutylcarbonyl]methylisothiourea
• CAS NO: 535952-65-9
• Molecular Weight: 817.914
• Mol File: 535952-65-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-N-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-N'-[2-(9-fluorenylmethoxycarbonyl)amino-4-phenylbutylcarbonyl]methylisothiourea(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-N'-[2-(9-fluorenylmethoxycarbonyl)amino-4-phenylbutylcarbonyl]methylisothiourea(535952-65-9)
• EPA Substance Registry System: (S)-N-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-N'-[2-(9-fluorenylmethoxycarbonyl)amino-4-phenylbutylcarbonyl]methylisothiourea(535952-65-9)

Safety Data

• Hazardous Substances Data: 535952-65-9(Hazardous Substances Data)

Upstream product

• 219967-74-5 (S)-3-(<<(9H-fluoren-9-yl)methoxy>carbonyl>amino)-5-phenylpentanoic acid 
• 535952-60-4 N-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)methylisothiourea 

Relevant articles and documents

Syntheses of guanidinoglycosides with the inventive use of Mitsunobu conditions and 1,8-diazabicyclo[5.4.0]undec-7-ene

A series of novel guanidinoglycosides was successfully synthesized. This was accomplished with the use of Mitsunobu conditions as a strategy to convert the glycopyranose anomeric hydroxy group to give the corresponding substituted masked guanidines in high yields. Subsequent deprotection and coupling with Fmoc protected β-amino acid, afforded a series of N,N′-substituted-methyl-isothioureas. Cleavage of Fmoc followed by concomitant cyclization was achieved with a catalytic amount of DBU to give the guanidinoglycosides.