5365-43-5

Basic information

• Product Name: Benzoic acid, 4-butoxy-, ethyl ester
• CAS NO: 5365-43-5
• Molecular Formula: C13H18O3
• Molecular Weight: 222.284
• Mol File: 5365-43-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 196-197.5 °C(Press: 31 Torr)
• Density: 1.022±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoic acid, 4-butoxy-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-butoxy-, ethyl ester(5365-43-5)
• EPA Substance Registry System: Benzoic acid, 4-butoxy-, ethyl ester(5365-43-5)

Safety Data

• Hazardous Substances Data: 5365-43-5(Hazardous Substances Data)

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 542-69-8 1-iodo-butane 
• 99-96-7 4-hydroxy-benzoic acid 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 71-36-3 butan-1-ol 
• 7335-27-5 ethyl 4-chlorobenzoate 
• 109-65-9 1-bromo-butane 

Downstream Products

• 1498-96-0 4-butoxybenzoic acid 
• 64328-61-6 (4-butyloxybenzoyl)hydrazine 
• 721426-56-8 C₁₂H₁₈N₂O₂ 
• 56800-29-4 4-formylphenyl 4-butyloxybenzoate 
• 1630012-94-0 4-butyl-5-(4-butoxyphenyl)-2H-1,2,4-triazole-3(4H)-one 
• 1410633-49-6 C₁₂H₁₄N₂O₃ 
• 901967-47-3 C₁₆H₂₅N₃O₃ 
• 1440507-28-7 tris[2-(4-butyloxybenzoyloxy)ethyl]amine 
• 98562-78-8 (2-Diethylamino-ethyl)-(4-butyloxy-phenylmethyl)-ether 
• 99857-20-2 4-butoxy-benzoyl azide 
• 33863-86-4 4-(n-butyloxy)benzoyl chloride 

Relevant articles and documents

Synthesis and mesomorphic characterization of some novel steroidal mesogens: A structure–property correlation

The steroidal derivatives are found to be extremely good mesogens since their inception. Because of their inherent chirality, they have the potential to induce a wide variety of liquid crystalline phases, including frustrated phases depending upon the structure of the steroidal skeleton and the substituents attached. In this report, a series of novel monoalkoxy and dialkoxy benzoate derivatives of ergosterol and a few monoalkoxy derivatives of stigmasterol have been synthesized and their mesomorphic property has been investigated. The derivatives exhibited various mesophases including SmA, SmC*, N*, TGB and blue phases. Also, the gelation ability of some of these derivatives with various organic solvents has been examined. Furthermore, the mesomorphism of these derivatives has been compared with the analogous cholesteryl counterparts.

Light-Promoted Nickel Catalysis: Etherification of Aryl Electrophiles with Alcohols Catalyzed by a NiII-Aryl Complex

A highly effective C?O coupling reaction of (hetero)aryl electrophiles with primary and secondary alcohols is reported. Catalyzed by a NiII-aryl complex under long-wave UV (390–395 nm) irradiation in the presence of a soluble amine base without any additional photosensitizer, the reaction enables the etherification of aryl bromides and aryl chlorides as well as sulfonates with a wide range of primary and secondary aliphatic alcohols, affording synthetically important ethers. Intramolecular C?O coupling is also possible. The reaction appears to proceed via a NiI–NiIII catalytic cycle.

Synthesis and anticonvulsant activity evaluation of 4-butyl-5-(4- alkoxyphenyl)-2H-1,2,4-triazole-3(4H)-ones

A series of 4-butyl-5-(4-alkoxyphenyl)-2H-1,2,4-triazole-3(4H)-ones (6a-6u) was designed and synthesized. The anticonvulsant effects and neurotoxicity of the compounds were evaluated with maximal electroshock test and rotarod test. Among the synthetic compounds, 4-butyl-5-(4-(2-fluorinebenzyl)phenyl)-2H-1,2,4- triazole-3 (4H)-one (6k) was the most potent with ED50 value of 27.4 mg/kg and protective index (PI = TD50/ED50) value of 12.0. Besides the anti-MES efficacy, the potency of compound 6k against seizures induced by pentylenetetrazole (PTZ), 3-mercaptopropionic acid (3-MP), and bicuculline (BIC) was also established, which suggested that the mechanisms of action including enhancing of GABAergic activity might be involved in its anticonvulsant activity.