5367-28-2 Usage
Description
5-Chloro-2-nitrotoluene is an analog of chlorphenamidine, characterized by its clear yellow liquid appearance. It is a chemical compound that has been studied for its cytotoxic properties, which means it has the potential to be harmful or destructive to living cells.
Uses
Used in Pharmaceutical Industry:
5-Chloro-2-nitrotoluene is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its cytotoxic properties make it a candidate for the development of drugs targeting cancer cells or other diseases where cell destruction is a therapeutic goal.
Used in Chemical Research:
As an analog of chlorphenamidine, 5-Chloro-2-nitrotoluene is used in chemical research to study its properties, reactions, and potential applications in the development of new compounds or materials. This can include exploring its use in the synthesis of dyes, pesticides, or other specialty chemicals.
Used in Material Science:
The cytotoxic properties of 5-Chloro-2-nitrotoluene may also find applications in material science, particularly in the development of materials with antimicrobial or antifungal properties. These materials could be used in various industries, such as healthcare, to prevent the growth of harmful microorganisms on surfaces.
Check Digit Verification of cas no
The CAS Registry Mumber 5367-28-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,6 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5367-28:
(6*5)+(5*3)+(4*6)+(3*7)+(2*2)+(1*8)=102
102 % 10 = 2
So 5367-28-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClNO2/c1-5-4-6(8)2-3-7(5)9(10)11/h2-4H,1H3
5367-28-2Relevant articles and documents
Nitration of deactivated aromatic compounds via mechanochemical reaction
Wu, Jian-Wei,Zhang, Pu,Guo, Zhi-Xin
supporting information, (2021/05/05)
A variety of deactivated arenes were nitrated to their corresponding nitro derivatives in excellent yields under high-speed ball milling condition using Fe(NO3)3·9H2O/P2O5 as nitrating reagent. A radical involved mechanism was proposed for this facial, eco-friendly, safe, and effective nitration reaction.
Highly efficient Sandmeyer reaction on immobilized CuI/CuII-based catalysts
Tarkhanova, Irina G.,Gantman, Michail G.,Sigeev, Alexander S.,Maslakov, Konstantin I.,Zelikman, Vladimir M.,Beletskaya, Irina P.
, p. 261 - 263 (2018/06/01)
Highly effective embodiment of Sandmeyer reaction has been revealed for Cu-based catalysts incorporating ionic liquid on Silochrom support. The most active catalyst (TOF = = 4000–8000 h–1) contains comparable amounts of cuprous and cupric chloride anions. The reported method allows one to carry out the reaction for anilines in the one-pot mode.
PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
-
Page/Page column 83, (2012/02/01)
Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.