53731-26-3 Usage
Description
1-(Difluoromethyl)naphthalene is a chemical compound with the molecular formula C11H8F2, belonging to the class of fluorinated derivatives of naphthalene, a polycyclic aromatic hydrocarbon. It is characterized by the presence of a fluoromethyl group attached to the naphthalene ring, which endows it with unique properties and potential applications across various fields.
Uses
Used in Organic Synthesis:
1-(Difluoromethyl)naphthalene is used as a building block in organic synthesis for the creation of more complex molecular structures. Its unique chemical properties and reactivity make it a valuable component in the development of new compounds with specific characteristics.
Used in Pharmaceutical Applications:
In the pharmaceutical industry, 1-(Difluoromethyl)naphthalene is utilized as a precursor for the production of compounds with potential therapeutic applications. Its fluorinated nature may contribute to enhanced bioavailability and pharmacokinetic properties of the resulting molecules.
Used in Agrochemical Applications:
1-(Difluoromethyl)naphthalene also finds use in the agrochemical sector, where it serves as a starting material for the synthesis of compounds with pesticidal or herbicidal activities. The introduction of fluorine atoms can significantly affect the biological activity and environmental fate of these agrochemicals.
Used in Materials Science:
In the field of materials science, 1-(Difluoromethyl)naphthalene is explored for its potential in developing novel materials with improved properties, such as increased stability, reactivity, or selectivity. Its unique structure and fluorination make it an interesting candidate for various applications, including the development of advanced materials for energy storage, sensors, or catalysts.
Overall, 1-(Difluoromethyl)naphthalene is a versatile compound with a wide range of potential applications in different industries, thanks to its unique chemical structure and reactivity. Researchers and industries are continuously exploring its potential to develop new compounds and materials with specific properties for various scientific and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 53731-26-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,7,3 and 1 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 53731-26:
(7*5)+(6*3)+(5*7)+(4*3)+(3*1)+(2*2)+(1*6)=113
113 % 10 = 3
So 53731-26-3 is a valid CAS Registry Number.
53731-26-3Relevant articles and documents
Electrochemical-Promoted Nickel-Catalyzed Oxidative Fluoroalkylation of Aryl Iodides
Zou, Zhenlei,Li, Heyin,Huang, Mengjun,Zhang, Weigang,Zhi, Sanjun,Wang, Yi,Pan, Yi
supporting information, p. 8252 - 8256 (2021/11/01)
This work describes a general strategy for metal-catalyzed cross-coupling of fluoroalkyl radicals with aryl halides under electrochemical conditions. The contradiction between anodic oxidation of fluoroalkyl sulfinates and cathodic reduction of low-valent nickel catalysts can be well addressed by paired electrolysis, allowing for direct introduction of fluorinated functionalities into aromatic systems.
Base-Catalyzed H/D Exchange Reaction of Difluoromethylarenes
Huang, Linwei,Liu, Wei,Zhao, Liang-Liang,Zhang, Zengyu,Yan, Xiaoyu
, p. 3981 - 3988 (2021/03/09)
The budding deuteriodifluoromethyl group (CF2D) is a potentially significant functional group in medicinal chemistry. Herein, we investigated t-BuOK-catalyzed H/D exchange reaction of difluoromethylarenes in DMSO-d6 solution. The method provides excellent
Deoxyfluorination of (Hetero)aryl Aldehydes Using Tetramethylammonium Fluoride and Perfluorobutanesulfonyl Fluoride or Trifluoromethanesulfonic Anhydride
Ferguson, Devin M.,Melvin, Patrick R.,Sanford, Melanie S.
, p. 398 - 401 (2019/09/06)
This Communication describes the conversion of (hetero)aryl aldehydes into the corresponding (hetero)aryl difluoromethyl products using anhydrous NMe4F in combination with perfluorobutanesulfonyl fluoride or trifluoromethanesulfonic anhydride.
