53934-76-2 Usage
Description
(2-OXOPYRROLIDIN-1-YL)ACETIC ACID is an organic compound that serves as a crucial reagent in the synthesis of various chemical compounds, particularly in the pharmaceutical industry. It is characterized by its unique chemical structure, which includes a pyrrolidinone ring and an acetic acid group, making it a versatile building block for the development of new drugs and other applications.
Uses
Used in Pharmaceutical Industry:
(2-OXOPYRROLIDIN-1-YL)ACETIC ACID is used as a reagent for the preparation of pyrazolopyridines, which are known as PDE4B inhibitors. These inhibitors play a significant role in the treatment of various inflammatory and autoimmune diseases by modulating the activity of phosphodiesterase 4B (PDE4B), an enzyme involved in the regulation of inflammatory processes. (2-OXOPYRROLIDIN-1-YL)ACETIC ACID's ability to facilitate the synthesis of these inhibitors makes it an essential component in the development of novel therapeutic agents for a wide range of medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 53934-76-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,9,3 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 53934-76:
(7*5)+(6*3)+(5*9)+(4*3)+(3*4)+(2*7)+(1*6)=142
142 % 10 = 2
So 53934-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H9NO3/c8-5-2-1-3-7(5)4-6(9)10/h1-4H2,(H,9,10)
53934-76-2Relevant articles and documents
Synthesis of N-Lauroyl Sarcosine by Amidocarbonylation: Comparing Homogeneous and Heterogeneous Palladium Catalysts
Hancker, S?ren,Kreft, Stefanie,Neumann, Helfried,Beller, Matthias
supporting information, p. 2045 - 2051 (2017/12/26)
An improved system for the synthesis of N-acyl amino acids via Pd-catalyzed amidocarbonylation is reported. Utilizing inexpensive Pd black gives the industrially important surfactant N-lauroyl sarcosine in excellent yields (95%) on a multi-gram scale. Advantages of the new system include reusability, decreased process temperature, and, importantly, drastically decreased co-catalyst loading.
ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS
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Page/Page column 30-31, (2010/04/23)
The invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds.
Facile synthesis of gold icosahedra in an aqueous solution by reacting HAuCl4 with N-vinyl pyrrolidone
Yavuz, Mustafa S.,Li, Weiyang,Xia, Younan
experimental part, p. 13181 - 13187 (2010/07/03)
Herein we describe a protocol that generates Au icosahedra in high yields by simply mixing aqueous solutions of HAuCl4 and N-vinyl pyrrolidone. Our mechanistic study reveals that water plays an important role in this synthesis: as a nucleophile