53935-71-0 Usage
Description
2-Chlorothiophene-3-carboxylic acid is an organic compound with the molecular formula C5H3ClO2S. It is structurally similar to 5-Chloro-2-thiophenecarboxylic acid, which is a metabolite of Rivaroxaban, a widely used anticoagulant medication.
Uses
Used in Pharmaceutical Industry:
2-Chlorothiophene-3-carboxylic acid is used as an intermediate compound in the synthesis of various pharmaceuticals, particularly those related to anticoagulant medications. Its structural similarity to the metabolite of Rivaroxaban makes it a valuable compound for further research and development in the field of blood clot prevention and treatment.
Used in Research and Development:
In the field of medicinal chemistry, 2-Chlorothiophene-3-carboxylic acid serves as a key building block for the development of new therapeutic agents. Its unique chemical properties allow researchers to explore its potential in creating novel drugs with improved efficacy and reduced side effects.
Used in Metabolite Studies:
As a structural analog of a metabolite of Rivaroxaban, 2-Chlorothiophene-3-carboxylic acid can be utilized in metabolite studies to better understand the metabolic pathways and pharmacokinetics of anticoagulant drugs. This knowledge can contribute to the optimization of drug dosages and the development of personalized treatment strategies for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 53935-71-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,9,3 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 53935-71:
(7*5)+(6*3)+(5*9)+(4*3)+(3*5)+(2*7)+(1*1)=140
140 % 10 = 0
So 53935-71-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H3ClO2S/c6-4-3(5(7)8)1-2-9-4/h1-2H,(H,7,8)
53935-71-0Relevant articles and documents
Synthesis and antitumour activity of new derivatives of flavone-8- acetic acid (FAA). Part 31): 2-Heteroaryl derivatives
Aitken, R. Alan,Bibby, Michael C.,Bielefeldt, Florian,Double, John A.,Laws, Andrea L.,Mathieu, Anne-Laure,Ritchie, Robert B.,Wilson, David W. J.
, p. 405 - 411 (2007/10/03)
A range of 14 derivatives of flavone-8-acetic acid (FAA) with a heterocyclic substituent in place of the 2-phenyl group have been prepared and their anti-tumour activity evaluated in vitro against a panel of human and murine tumour cell lines and in vivo against MAC 15A. Some of the compounds, notably 2c,d and s, showed significant in vivo activity and these require further studies in order to evaluate their potential for development.
Heterobicyclic sulfonamides
-
, (2008/06/13)
Compounds of general formula: STR1 are topically effective carbonic anhydrase inhibitors useful in the treatment of ocular hypertension and related disorders such as glaucoma.
