5402-60-8

Basic information

• Product Name: 2,6-Dimethylbenzyl chloride
• Synonyms: 1-CHLOROMETHYL-2,6-DIMETHYLBENZENE;2-CHLOROMETHYL-1,3-DIMETHYL-BENZENE;2,6-DIMETHYLBENZYL CHLORIDE;2-(Chloromethyl)-1,3-dimethylbenzene, 2-(Chloromethyl)-m-xylene;[(2,6-diMethylphenyl)Methyl]chloranuide
• CAS NO: 5402-60-8
• Molecular Formula: C₉H₁₁Cl
• Molecular Weight: 154.64
• Product Categories: Benzene derivatives
• Mol File: 5402-60-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: 33-35°C
• Boiling Point: 70°C 5mm
• Flash Point: 33 °C
• Appearance: /
• Density: 1.033 g/cm³
• Vapor Pressure: 0.132mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,6-Dimethylbenzyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethylbenzyl chloride(5402-60-8)
• EPA Substance Registry System: 2,6-Dimethylbenzyl chloride(5402-60-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3261
• HazardClass: IRRITANT, LACHRYMATOR
• Hazardous Substances Data: 5402-60-8(Hazardous Substances Data)

Usage

General Description

2,6-Dimethylbenzyl chloride is a chemical compound with the formula C9H11Cl. It is a colorless to pale yellow liquid with a strong, pungent odor. This chemical is commonly used as an intermediate in the production of various pharmaceuticals, agrochemicals, and dyes. It acts as a key building block in the synthesis of other organic compounds, particularly in the manufacturing of insecticides and disinfectants. 2,6-Dimethylbenzyl chloride also exhibits some degree of toxicity and should be handled with caution in a well-ventilated environment. Overall, it serves a crucial role as a versatile chemical intermediate in a variety of industrial processes.

InChI:InChI=1/C9H11Cl/c1-7-4-3-5-8(2)9(7)6-10/h3-5H,6H2,1-2H3

Upstream product

• 62285-58-9 2,6-dimethylbenzyl alcohol 
• 7093-91-6 chloromethyl isocyanate 
• 108-38-3 m-xylene 
• 50-00-0 formaldehyd 
• 632-46-2 2,6-dimethylbenzoic acid 
• 1123-56-4 2,6-dimethylbenzaldehyde 
• 87-62-7 2,6-dimethylaniline 
• 608-28-6 2,6-dimethyliodobenzene 

Downstream Products

• 15855-51-3 N,N-diethyl-N'-(2,6-dimethyl-benzyl)-ethylenediamine 
• 54708-14-4 2,6-dimethylphenylacetonitrile 
• 51445-98-8 o,o'-Dimethylbenzylnitrat 
• 19289-31-7 3-<2,6-Dimethyl-benzyloxy>-3-methyl-acrylsaeureethylester 
• 902526-55-0 Diaethyl-2,6-dimethylbenzylphosphonat 
• 540524-67-2 (2,6-dimethylphenyl)methanesulfonyl chloride 
• 130403-21-3 2-(2,6-di-methylbenzyl)isoindoline-1,3-dione 
• 1027398-50-0 [2-cyano-5-(2,6-dimethyl-benzyloxy)-phenoxy]-o-tolyl-acetic acid methyl ester 
• 51739-98-1 2,6-dimethylbenzyl radical 
• 1001096-12-3 C₂₄H₃₀NO₄P 
• 74788-82-2 (2,6-dimethylphenyl)methanamine 
• 186538-17-0 (R)-N-(2,6-dimethylbenzyl)-1,3-thiazolidine-4-carboxamide 
• 1027226-32-9 4-(2,6-dimethyl-benzylcarbamoyl)-thiazolidine-3-carboxylic acid tert-butyl ester 
• 226997-95-1 (R)-N-(2,6-dimethylbenzyl)-3-<(2S,3S)-3-amino-2-hydroxy-4-phenylbutanoyl>-1,3-thiazolidine-4-carboxamide 

Relevant articles and documents

PROCESS FOR PREPARING 2,6-DIALKYLPHENYLACETIC ACIDS

The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5

BENZODIAZEPINONE COMPOUNDS USEFUL IN THE TREATMENT OF SKIN CONDITIONS

The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.

Synthesis and molecular structures of zirconium and hafnium complexes bearing dimethylsilandiyl-bis-2,4,6-trimethylindenyl and dimethylsilandiyl-bis- 2-methyl-4,6-diisopropylindenyl ligands

Zirconium and hafnium ansa-complexes containing 2,4,6-trialkyl-substituted indenyl fragments were synthesized and unambiguously characterized. Mixtures of rac- and meso-Me2Si(2-Me-4,6-R2C9H 3-η5)2MCl2, where R = Me, i-Pr and M = Zr, Hf, were obtained by a treatment of MCl4 by dilithium salts of the respective bis(2,4,6-trialkylindenyl)dimethylsilanes in toluene. Alternatively, better yields of the same complexes can be obtained by the reaction between metal tetrachlorides and indenyl-tin derivatives gave the desired ansa-metallocenes. All rac- and meso-complexes of Zr and Hf were isolated in an analytically pure form, and six of these ansa-metallocenes were characterized by X-ray crystal structure analysis.