54167-76-9 Usage
Description
N-(2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, a chemical compound belonging to the imidazo[1,2-a]pyridine class, is an acetamide derivative with the molecular formula C16H14N4O. Its unique molecular structure endows it with potential pharmaceutical applications, making it a promising candidate for the development of biologically active molecules and therapeutic agents.
Uses
Used in Pharmaceutical Applications:
N-(2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetamide is used as a building block in the synthesis of various biologically active molecules due to its structural properties. Its specific molecular structure allows for interactions with specific targets in biological systems, making it a potentially useful compound in drug development.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-(2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetamide is used as a starting point for the development of new therapeutic agents. Its properties as an imidazo[1,2-a]pyridine derivative make it of interest for further research and potential applications in creating novel drugs with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 54167-76-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,1,6 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 54167-76:
(7*5)+(6*4)+(5*1)+(4*6)+(3*7)+(2*7)+(1*6)=129
129 % 10 = 9
So 54167-76-9 is a valid CAS Registry Number.
54167-76-9Relevant articles and documents
Exploration of versatile reactions on 2-chloro-3-nitroimidazo[1,2-a] pyridine: Expanding structural diversity of C2- and C3-functionalized imidazo[1,2-a]pyridines
Bazin, Marc-Antoine,Marhadour, Sophie,Tonnerre, Alain,Marchand, Pascal
, p. 5378 - 5382 (2013/09/12)
Alternative strategies for functionalizing 2-chloro-3-nitroimidazo[1,2-a] pyridine have been developed. Suzuki-Miyaura cross-coupling reaction provided easily the corresponding 2-arylated compounds, and herefrom the nitro group was reduced into amine which afforded amides, anilines, and ureas in the 3-position. The amination of the key compound using a metal-catalyzed reaction was reported. This study highlighted the importance of the nitro group to facilitate the chlorine displacement. Other nucleophilic aromatic substitutions open a route to various products derived from imidazo[1,2-a]pyridine.
EFFECTIVE STRATEGY FOR THE SYNTHESIS OF PYRIDOIMIDAZOISOQUINOLINE SYSTEM
Chavignon, Olivier,Raihane, Mohamed,Deplat, Patricia,Chabard, Jean Louis,Gueiffier, Alain,et al.
, p. 2019 - 2026 (2007/10/03)
Annulation of 3-aceta(benza)mido-2-phenylimidazopyridines (2a,b) by phosphorus oxychloride results in the formation of pyridoimidazoisoquinolines (3a,b) as potent antileukemic structures.An alternative route for obtaining the isoquinoline framework was centered on the aza-Wittig reaction of iminophosphorane (4) with different isocyanates.
