54187-03-0 Usage
Description
1-(2-chloroethyl)-3-(dicyclopropylmethyl)urea, also known as N-(dicyclopropylmethyl)-N''-(2-chloroethyl)urea, is a chemical compound with the molecular formula C10H16ClN3O2. It is a metabolite derived from Rilmenidine (R509710), which is an imidazoline I1-receptor agonist. 1-(2-chloroethyl)-3-(dicyclopropylmethyl)urea plays a significant role in the pharmaceutical industry due to its association with the treatment of hypertension.
Uses
Used in Pharmaceutical Industry:
1-(2-chloroethyl)-3-(dicyclopropylmethyl)urea is used as a metabolite in the treatment of hypertension for its association with Rilmenidine (R509710). As an imidazoline I1-receptor agonist, it helps regulate blood pressure and contributes to the management of hypertension in patients.
Used in Research and Development:
1-(2-chloroethyl)-3-(dicyclopropylmethyl)urea is also utilized in research and development for understanding the metabolic pathways and pharmacological effects of Rilmenidine. It aids in the study of the drug's mechanism of action, potential side effects, and its overall impact on the treatment of hypertension.
Check Digit Verification of cas no
The CAS Registry Mumber 54187-03-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,1,8 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 54187-03:
(7*5)+(6*4)+(5*1)+(4*8)+(3*7)+(2*0)+(1*3)=120
120 % 10 = 0
So 54187-03-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H17ClN2O/c11-5-6-12-10(14)13-9(7-1-2-7)8-3-4-8/h7-9H,1-6H2,(H2,12,13,14)
54187-03-0Relevant articles and documents
Cyclopropylamines as pharmaceuticals
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, (2008/06/13)
The present invention relates to cyclopropylmethyl amines substituted by a heterocyclic radical. More particularly the heterocyclic radical is a nitrogen containing ring with 5, 6 or 7 links interrupted by another hetero atom selected from the group consisting of oxygen, sulphur and imino--NH-- The invention also relates to the acid addition salts thereof with physiologically compatible mineral or organic acids. The invention extends to the processes for making them and the intermediates produced hereto. The invention also includes the pharmaceutical compositions incorporating as active ingredient at least one compound of the invention with an inert carrier. The compounds have therapeutic utility namely on the cardio-vascular diseases and on the neuro-psychological disturbances.
