5422-45-7Relevant articles and documents
Fimctlonalized tetrazoles from cyanogen azide with secondary amines
Joo, Young-Hyuk,Shreeve, Jean'ne M.
experimental part, p. 3573 - 3578 (2009/10/26)
Secondary amines react with cyanogen azide at ambient temperature in water/acetonitrile to provide tetrazole derivatives directly. The scope and limitations with regard to steric hindrance of the amine are discussed. Although reaction yields are moderate, 29-81%, the cyanogen azide reactions provide a direct and versatile route to functionalized tetrazoles that: may be especially useful considering the diversity of amines suitable for this transformation.