5433-39-6

Basic information

• Product Name: N-(3-pyridinylcarbonyl)benzenesulfonohydrazide
• CAS NO: 5433-39-6
• Molecular Formula: C₁₂H₁₁N₃O₃S
• Molecular Weight: 277.304
• Mol File: 5433-39-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.376g/cm³
• CAS DataBase Reference: N-(3-pyridinylcarbonyl)benzenesulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-pyridinylcarbonyl)benzenesulfonohydrazide(5433-39-6)
• EPA Substance Registry System: N-(3-pyridinylcarbonyl)benzenesulfonohydrazide(5433-39-6)

Safety Data

• Hazardous Substances Data: 5433-39-6(Hazardous Substances Data)

Usage

Description

N-(3-pyridinylcarbonyl)benzenesulfonohydrazide is a chemical compound with the molecular formula C13H11N3O3S. It is a hydrazide derivative featuring a pyridine ring attached to a benzene ring, along with a sulfonohydrazide group. N-(3-pyridinylcarbonyl)benzenesulfonohydrazide has been utilized as a reagent in the synthesis of pharmaceuticals and agrochemicals, and it has demonstrated potential anti-inflammatory, analgesic, and anticancer properties, positioning it as a candidate for drug development.

Uses

Used in Pharmaceutical Industry:
N-(3-pyridinylcarbonyl)benzenesulfonohydrazide is used as a reagent for the synthesis of various pharmaceuticals due to its unique chemical structure and properties.
Used in Agrochemical Industry:
N-(3-pyridinylcarbonyl)benzenesulfonohydrazide is also used as a reagent in the synthesis of agrochemicals, contributing to the development of new products for agricultural applications.
Used in Drug Development:
N-(3-pyridinylcarbonyl)benzenesulfonohydrazide is used as a candidate for drug development because of its potential anti-inflammatory and analgesic properties, which could be harnessed to create new medications for pain relief and inflammation management.
Used in Oncology Research:
In the field of oncology, N-(3-pyridinylcarbonyl)benzenesulfonohydrazide is used as a subject of research for its promising anticancer activity, with potential applications in developing new cancer treatments.

Upstream product

• 93-60-7 methyl 3-pyridinecarboxylate 
• 553-53-7 Nicotinic acid hydrazide 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 66310-17-6 3-benzoyloxymethyl-1-methyl-pyridinium; iodide 
• 13441-54-8 3-formylpyridinium methiodide 
• 58550-50-8 pyridin-3-ylmethyl benzoate 
• 17470-24-5 2-amino-3-(pyridin-3-yl)propanoic acid 
• 100-55-0 3-hydroxymethylpyridin 
• 882-33-7 diphenyldisulfane 
• 500-22-1 3-pyridinecarboxaldehyde 
• 109966-43-0 pyridine-3-carbaldehyde-(4-o-tolyl thiosemicarbazone) 
• 110029-19-1 pyridine-3-carbaldehyde-(4-p-tolyl thiosemicarbazone) 
• 107681-96-9 pyridine-3-carbaldehyde-[4-(2-methoxy-phenyl)-thiosemicarbazone] 
• 107682-76-8 pyridine-3-carbaldehyde-[4-(4-methoxy-phenyl)-thiosemicarbazone] 

Relevant articles and documents

Synthesis of N'-nicotinoyl sulfonohydrazides and their antimicrobial activity

N'-Nicotinoyl sulfonohydrazide derivatives 3-13 were synthesized from nicotinyl hydrazide and evaluated for their antimicrobial potential against Gram positive bacterial strains (Bacillus cereus, Bacillus subtilis, Corynebacterium diphtheriae, Staphylococcus fecalis, Staphylococcus aureus, and MRSA (Methicillin-resistant Staphylococcus aureus)) and Gram negative bacterial strains (Escherichia.coli, Pseudomonas aeruginosa, Salmonella ParatyphiB, Salmonella tyhpi). Compound 13 showed outstanding antibacterial activity against Staphylococcus fecalis and compounds 7 and 13 were found to be moderately activite against Salmonella Paratyphi B, shown by their zone of inhibition values. In addition to that compond 9 also showed moderate activity against Escherichia coli. All derivatives 3-13 were also subjected for the evaluation of their antifungal activity against Saccharomyces cerevisiae, Microsporum canin, Rhizopus, Aspergillus niger, Candida albicans, and Candida tropicalis. Compound 13 showed promising antifungal activity against Rhizopus sp. and compounds 9 and 10 showed moderate antifungal potential against Microsporum canis, Aspergillus niger, and Candida tropicalis. Other molecules demonstrated weak zone of inhibitions.