54390-97-5

Basic information

• Product Name: 5-Bromoisothiazole
• Synonyms: 5-Bromoisothiazole ;Isothiazole, 5-bromo-
• CAS NO: 54390-97-5
• Molecular Formula: C₃H₂BrNS
• Molecular Weight: 164.0237
• Mol File: 54390-97-5.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 85.581 °C at 760 mmHg
• Flash Point: 5.56 °C
• Appearance: /
• Density: 1.857 g/cm³
• Vapor Pressure: 77.191mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5-Bromoisothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromoisothiazole(54390-97-5)
• EPA Substance Registry System: 5-Bromoisothiazole(54390-97-5)

Safety Data

• Hazardous Substances Data: 54390-97-5(Hazardous Substances Data)

Usage

Description

5-Bromoisothiazole is an organic compound that is a derivative of isothiazole, a versatile building block in the synthesis of various chemical compounds. It possesses a bromine atom at the 5th position, which contributes to its unique chemical properties and potential applications.

Uses

Used in Pharmaceutical Industry:
5-Bromoisothiazole is used as a synthetic intermediate for the development of 4-nitroisothiazoles, which have potential antifungal properties. These compounds can be utilized in the creation of new antifungal agents to combat fungal infections.
Used in Chemical Synthesis:
As a derivative of isothiazole, 5-Bromoisothiazole serves as a valuable building block in the synthesis of a wide range of chemical compounds. Its unique structure and functional groups make it a useful component in the development of new molecules with various applications across different industries.

InChI:InChI=1/C3H2BrNS/c4-3-1-2-5-6-3/h1-2H

Upstream product

• 288-16-4 isothiazol 

Downstream Products

• 1021937-60-9 C₂₀H₂₅N₃S 
• 1022155-24-3 1-[4-(2,2-dimethylpropyl)-1-trityl-1H-imidazol-2-yl]-2-(4-isothiazol-5-ylphenyl)propan-2-ol 
• 675109-06-5 8-isothiazol-5-yl-3-(5-methyl-3-phenylisoxazol-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole 

Relevant articles and documents

IMIDAZO [1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted imidazo[1,5-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,5-a]pyrimidinyl carboxamide compounds described herein include substituted 2-heterocyclyl-4-alkyl-imidazo[1,5-a]pyrirnidine-8-carboxamide compounds and variants thereof.

Injection pharmaceutical composition for vascular endothelial growth factor inhibitor

The invention belongs to the field of medicine, particularly relates to an injection pharmaceutical composition for inhibiting salt of a compound of formula I (shown in the description) of a VEGF, pharmaceutical use of the injection pharmaceutical composition and a pharmaceutical preparation and particularly aims at treatment of tumors and angiogenesis. The invention further relates to a synthetic method of the compound.

Vascular endothelial growth factor inhibitor compound

The invention relates to a vascular endothelial growth factor inhibitor compound. The invention belongs to the medical field and particularly relates to salt of a compound of formula I (shown in the description). The invention further relates to synthetic method of the compound, pharmaceutical use of the compound and a pharmaceutical preparation and particularly aims at treatment of tumors and angiogenesis.