54535-00-1

Basic information

• Product Name: (5,7-dimethyl-3H-8lambda~5~-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol
• Synonyms: (5,7-dimethyl-3H-8lambda~5~-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol;(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol(SALTDATA: FREE)
• CAS NO: 54535-00-1
• Molecular Formula: C8H10N4O
• Molecular Weight: 178.2
• Mol File: 54535-00-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Density: 1.428 g/cm³
• Refractive Index: 1.694
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 12.76±0.10(Predicted)
• CAS DataBase Reference: (5,7-dimethyl-3H-8lambda~5~-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (5,7-dimethyl-3H-8lambda~5~-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol(54535-00-1)
• EPA Substance Registry System: (5,7-dimethyl-3H-8lambda~5~-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol(54535-00-1)

Safety Data

• Hazardous Substances Data: 54535-00-1(Hazardous Substances Data)

Usage

General Description

"(5,7-dimethyl-3H-8lambda~5~-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol" is a chemical compound with a molecular formula C9H10N4O. It is a pyrimidine derivative containing a triazolopyrimidine ring system. (5,7-dimethyl-3H-8lambda~5~-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol is used in the field of medicinal chemistry and pharmaceutical research for the development of new drugs and potential therapeutic agents. Its exact biological and pharmacological properties are not fully elucidated, but it is likely to exhibit some level of biological activity due to its structural features. Further research may uncover its potential applications and uses in the medical and pharmaceutical fields.

InChI:InChI=1/C8H10N4O/c1-5-3-6(2)12-8(9-5)10-7(4-13)11-12/h3,13H,4H2,1-2H3

Upstream product

• 27277-03-8 5-amino-3-hydroxymethyl-1H-1,2,4-triazole 
• 123-54-6 acetylacetone 
• 63870-39-3 (5-amino-1H-[1,2,4]triazol-3-yl)-methanol; glycolate 
• 55293-96-4 5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carbaldehyde 
• 1508308-97-1 C₂₉H₃₆⁽²⁾HN₅O₃ 
• 87253-62-1 5,7-dimethyl-1,2,4-triazolo<1,5-a>pyrimidine-2-carboxylic acid 

Downstream Products

• 55293-96-4 5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carbaldehyde 
• 1383385-86-1 C₂₆H₃₂IN₅O₂S 
• 1510832-76-4 C₁₀H₁₂N₄O₂*ClH 
• 1510832-81-1 C₄₀H₄₄N₆O₇ 
• 1510832-83-3 C₄₂H₄₈N₆O₇ 
• 1201687-89-9 2-(chloromethyl)-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine 
• 7637-33-4 2,5,7-Trimethyl-s-triazolo<1,5-a>pyrimidin 

Relevant articles and documents

Imidazo[4,5-c]pyridine derivative and application thereof

The invention relates to a novel imidazo[4,5-c]pyridine derivative represented by a general formula I, and pharmaceutically acceptable salts, solvates or prodrugs of the novel imidazo[4,5-c]pyridine derivative, wherein the substituent R and R' are defined as in the specification. The invention also relates to an effect of the compound represented by the general formula I in inhibiting an NS5B RNA-dependent RNA polymerase (NS5B polymerase for short) which is necessary in a replication process of hepatitis c virus, also relates to an application of the compound, and pharmaceutically acceptable salts, hydrates or prodrugs of the compound in preparation of medicines for treating viral diseases, and especially relates to an application in preparation of medicines for treating and/or preventinghepatitis c.

IMIDAZOLE DERIVATIVES

The present invention relates to compounds of formula (I), wherein A, B, R1 and R2 are as defined herein before.

INHIBITORS OF HEPATITIS C VIRUS POLYMERASE

The present invention provides, among other things, compounds represented by the general Formula (I) and pharmaceutically acceptable salts thereof, wherein X, Y, R1A, R1B, R2, and R3 are as defined in classes and subclasses herein and compositions (e.g., pharmaceutical compositions) comprising such compounds, which compounds are useful as inhibitors of hepatitis C virus polymerase, and thus are useful, for example, as medicaments for the treatment of HCV infection.