54681-67-3

Basic information

• Product Name: Ethyl Acetamidomalonate
• Synonyms: 2-(Acetylamino)propanedioic acid 1-ethyl ester;2-AcetaMido-3-ethoxy-3-oxopropanoic acid
• CAS NO: 54681-67-3
• Molecular Formula: C₇H₁₁NO₅
• Molecular Weight: 189.17
• Mol File: 54681-67-3.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Density: 1.273
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Ethyl Acetamidomalonate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl Acetamidomalonate(54681-67-3)
• EPA Substance Registry System: Ethyl Acetamidomalonate(54681-67-3)

Safety Data

• Hazardous Substances Data: 54681-67-3(Hazardous Substances Data)

Usage

General Description

Ethyl Acetamidomalonate is a chemical compound with the molecular formula C8H11NO5. It is commonly used as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Ethyl Acetamidomalonate is a white solid with a melting point of around 75-77°C and is soluble in organic solvents such as ethanol and acetone. It is also known for its ability to undergo a variety of chemical reactions, including condensation, hydrolysis, and esterification. This versatile compound has a wide range of applications in the field of chemical research and production.

Upstream product

• 1068-90-2 2-acetylaminomalonic acid diethyl ester 

Downstream Products

• 57332-78-2 5-methyl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylic acid ethyl ester 
• 5431-93-6 ethyl 2-(acetylamino)-3-oxobutanoate 
• 37946-91-1 N-Acetyl-3-(4-chlor-phenyl)-serin-ethylester 
• 107415-25-8 N-Acetyl-3-(2-chlor-phenyl)-serin-ethylester 
• 1219351-68-4 N-Acetyl-3-(4-nitro-phenyl)-serin-ethylester 
• 93003-95-3 Acetamino--essigsaeure-ethylester 
• 105540-35-0 N-Acetyl-oxamidsaeure-ethylester-(2-nitro-phenylhydrazon) 
• 95174-91-7 N-Acetyl-oxamidsaeure-ethylester-(2-chlor-phenylhydrazon) 
• 97406-07-0 N-Acetyl-oxamidsaeure-ethylester-(4-ethoxycarbonyl-phenylhydrazon) 
• 5872-81-1 N-Acetyl-3-(2-nitro-phenyl)-serin-ethylester 
• 96296-35-4 N-Acetyl-oxamidsaeure-ethylester-<4-nitro-2-methyl-phenylhydrazon> 
• 109038-04-2 N-Acetyl-3-<4-carbomethoxy-phenyl>-serin-ethylester 
• 1421-04-1 2,4-diaminopentanedioic acid 
• 96296-36-5 N-Acetyl-oxamidsaeure-ethylester-(4-nitro-2-methoxyphenylhydrazon) 

Relevant articles and documents

Stereoselective synthesis of dehydroamino acids using malonic acid half oxyester and aromatic aldehydes

An efficient and direct approach was developed for the synthesis of α,β-dehydroamino acid derivatives with a broad range of substrates. Amido-substituted Malonic Acid Half Oxyesters (MAHOs) have proven to be excellent partners of various aromatic aldehyde

MACROCYCLIC INHIBITORS OF HEPATITIS C PROTEASE

The invention provides compounds inhibitory to the Hepatitis C viral protease, compositions and combinations including the compounds, methods of treatment of conditions wherein inhibition of the Hepatitis C viral protease is medically indicated, and metho

Synthesis of BILN 2061, an HCV NS3 protease inhibitor with proven antiviral effect in humans

(Equation Presented) The synthesis of BILN 2061, an NS3 protease inhibitor with proven antiviral effect in humans, was accomplished in a convergent manner from four building blocks. The procedure described here was suitable for the preparation of multigra