5469-24-9

Basic information

• Product Name: methyl 2,3-dibromobutanoate
• Synonyms: Butanoic acid, 2,3-dibromo-, methyl ester
• CAS NO: 5469-24-9
• Molecular Formula: C₅H₈Br₂O₂
• Molecular Weight: 259.92
• Mol File: 5469-24-9.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 206.8°C at 760 mmHg
• Flash Point: 78.9°C
• Appearance: /
• Density: 1.834g/cm³
• Vapor Pressure: 0.233mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: methyl 2,3-dibromobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3-dibromobutanoate(5469-24-9)
• EPA Substance Registry System: methyl 2,3-dibromobutanoate(5469-24-9)

Safety Data

• Hazardous Substances Data: 5469-24-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H8Br2O2/c1-3(6)4(7)5(8)9-2/h3-4H,1-2H3

Upstream product

• 67-56-1 methanol 
• 600-30-6 erythro-2,3-dibromobutanoic acid 
• 623-43-8 methyl crotonate 
• 4358-59-2 (Z)-methyl but-2-enoate 
• 623-43-8 crotonic acid methyl ester 

Downstream Products

• 31907-99-0 1-benzyl-3-methyl-aziridine-2-carboxylic acid methyl ester 
• 17642-18-1 methyl bromo-crotonate 
• 17642-18-1 (E)-α-bromocrotonate de methyle 
• 623-43-8 crotonic acid methyl ester 
• 623-42-7 butanoic acid methyl ester 
• 55212-79-8 3-Pyrrolidino-2-butensaeure-methylester 
• 1093350-47-0 3-(phenylsulfanyl)but-2-enoic acid methyl ester 
• 17642-18-1 methyl α-bromocrotonate 

Relevant articles and documents

PROCESS FOR THE SYNTHESIS OF S-BEFLUBUTAMID USING ASYMMETRIC HYDROGENATION

Disclosed is a method for preparing compound S-1, from compound S-5; wherein compound S-5 is prepared by treating compound 2 with a tertiary amine and a hydrogen source in the presence of a chiral complex.

Reaction of Vinyl Aziridines with Arynes: Synthesis of Benzazepines and Branched Allyl Fluorides

We report the cycloaddition between vinyl aziridines and arynes. Depending on the reaction conditions and the choice of the aryne precursor, the aziridinium intermediate can be trapped through two distinct mechanistic pathways. The first one proceeds through a formal [5+2] cycloaddition to furnish valuable multi-substituted benzazepines. In the second pathway, the aziridinium is intercepted by a fluoride ion to afford allylic fluorides in good yields. Both reactions proceed stereospecifically and furnish enantiopure benzazepines and allylic fluorides.

Anionic [4+3] heteroannulation of 2-azidoacrylates: A modular synthesis of 2-benzazepin-1-ones

2-Azidoacrylates undergo [4+3] annulation with phthalides under anionic conditions at low temperatures to furnish 5-hydroxy-2-benzazepinones, the formation of which represents a new concept for the construction of azepines as well as a new reactivity of 2-azidoacrylates.