54737-66-5 Usage
General Description
2-(4-Phenoxyphenyl)propan-2-aMine, also known as PPTAM, is a chemical compound belonging to the class of amines. It is a white solid with a molecular formula C15H17NO and a molecular weight of 231.30 g/mol. PPTAM is a derivative of the amphetamine compound and has been studied for its potential pharmacological properties. It is known for its selective binding to the serotonin transporter and has shown to have antidepressant-like effects in animal models. PPTAM has also been investigated for its potential use in the treatment of various neurological disorders. Additionally, it has been studied for its potential role as a ligand in the development of new drugs targeting the serotonin system.
Check Digit Verification of cas no
The CAS Registry Mumber 54737-66-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,7,3 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 54737-66:
(7*5)+(6*4)+(5*7)+(4*3)+(3*7)+(2*6)+(1*6)=145
145 % 10 = 5
So 54737-66-5 is a valid CAS Registry Number.
54737-66-5Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS
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Paragraph 0591; 0593, (2020/07/16)
The present disclosure relates generally to compounds useful in treatment of conditions associated with mutant isocitrate dehydrogenase (mt-IDH), particularly mutant IDH1 enzymes. Specifically, the present invention discloses compound of formula (IA), which exhibits inhibitory activity against mutant IDH1 enzymes. Method of treating conditions associated with excessive activity of mutant IDH1 enzymes with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.