54745-74-3

Basic information

• Product Name: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE
• Synonyms: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE;8-Oxa-3-azabicyclooctaneHCl;8-Oxa-3-azabicyclo[3.2.1]octane monohydrochloride;8-Oxa-3-azabicyclo[3.2.1]octane, HCl;8-OXA-3-AZABICYCLO[3.2.1];8-Oxa-3-azabicyclo[3.2.1]octane,hydrochloride (1:1);8-oxa-3-azabicyclo[3.2.1]octane HCl salt
• CAS NO: 54745-74-3
• Molecular Formula: C₆H₁₁NO*ClH
• Molecular Weight: 149.62
• Product Categories: Heterocycles series;Fused Ring Systems
• Mol File: 54745-74-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 197-199 °C
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE(54745-74-3)
• EPA Substance Registry System: 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE(54745-74-3)

Safety Data

• Hazardous Substances Data: 54745-74-3(Hazardous Substances Data)

Usage

Description

8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE is a chemical compound that serves as a crucial intermediate in various organic synthesis processes. It is characterized by its unique bicyclic structure and hydrochloride salt form, which contributes to its versatility in chemical reactions and applications across different industries.

Uses

Used in the Agrochemical Industry:
8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE is used as an important raw material and intermediate for the synthesis of various agrochemicals. Its role in this industry is to facilitate the development of new and improved pesticides, herbicides, and other agricultural chemicals that can enhance crop protection and yield.
Used in the Pharmaceutical Industry:
In the pharmaceutical sector, 8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE is utilized as a key intermediate in the synthesis of a wide range of pharmaceutical compounds. Its unique chemical properties allow for the creation of new drugs with potential therapeutic applications, contributing to the advancement of medical treatments and healthcare solutions.
Used in the Dyestuff Industry:
8-OXA-3-AZABICYCLO[3.2.1]OCTANEHYDROCHLORIDE also plays a significant role in the dyestuff industry, where it is employed as a vital raw material and intermediate for the production of various dyes and pigments. Its involvement in this industry helps in the development of new and innovative colorants for a diverse array of applications, including textiles, plastics, and printing inks.

InChI:InChI=1/C6H11NO.ClH/c1-2-6-4-7-3-5(1)8-6;/h5-7H,1-4H2;1H

Upstream product

• 54745-75-4 3-benzyl-8-oxa-3-aza-bicyclo[3.2.1]octane 
• 3238-40-2 furan-2,5-dicarboxylic acid 

Downstream Products

• 54745-78-7 3-(4-chloro-benzoyl)-8-oxa-3-aza-bicyclo[3.2.1]octane 
• 60626-59-7 3-(adamantane-1-carbonyl)-8-oxa-3-aza-bicyclo[3.2.1]octane 
• 54745-77-6 3-phenylacetyl-8-oxa-3-aza-bicyclo[3.2.1]octane 
• 1127238-34-9 13-cyclohexyl-6-[1-ethyl-3-methyl-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-ylcarbonyl)-1H-pyrazol-5-yl]-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 
• 1127238-02-1 13-cyclohexyl-3-methoxy-N-[(1-methylethyl)sulfonyl]-6-[1-methyl-4-(8-oxa-3-azabicyclo[3.2.1]-oct-3-ylcarbonyl)-1H-pyrazol-5-yl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 
• 1144075-91-1 1-(1-benzyl-piperidin-4-yl)-6-chloro-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1144080-11-4 6-chloro-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1130155-02-0 3-chloro-5-({7-[(2E)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)but-2-enoyl]-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl}amino)phenol 
• 1195779-83-9 6-[1-cyclobutyl-4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)carbonyl-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 
• 1195780-43-8 6-[1-cyclobutyl-3-methyl-4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylcarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 
• 1204413-24-0 C₂₄H₂₅F₂N₇O₂ 
• 1144080-43-2 C₁₉H₁₇F₃N₆O₃ 
• 1144080-00-1 6-Chloro-1-ethyl-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1144080-48-7 6-chloro-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidine 

Relevant articles and documents

Concise syntheses of bridged morpholines

Concise and practical syntheses of 8-oxa-3-aza-bicyclo[3.2.1]octane and 9-oxa-3-aza-bicyclo[3.3.1]nonane are described starting from furan-2,5-dicarboxylic acid and 4H-pyran-2,6-dicarboxylic acid, respectively, and using a solvent-free step for a key cyclisation.

8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals

Disclosed are compounds, having the following general formula, which are useful as analgesics in living animals. SPC1 Wherein R is a radical selected from the group consisting of aralkyl, aryl, aminoalkyl, arylalkanoyl, heteroaroyl, alkoxy substituted aroyl, alkenyl (C2 to C4), halogen substituted aralkyl, guanadinoalkyl, halogen substituted aroyl, alkyl substituted aroyl, halogen substituted arylalkanoyl, hexahydrobenzoyl, arylalkenoyl, o- or p-alkyl substituted phenylalkanoyl, alkyl substituted naphthylalkanoyl, alkanoyl (C3 to C20), haloalkyl substituted aroyl, alkoxy substituted aralkyl, heteroaralkyl, anilinocarbonyl, adamantanecarbonyl, arylsulfonyl, carboxyl substituted aroyl, hydroxyl substituted aroyl, alkanoyloxy substituted aroyl, arylglyoxylyl, alicyclic, arylene dicarbonyl-8-oxa-3-azabicyclo(3.2.1)octane, alkylene-8-oxa-3-azabicyclo (3.2.1)octane, alkylene dicarbonyl-8-oxa-3-azabicyclo(3.2.1)octane, and the pharmacologically acceptable acid addition salts thereof.