54887-23-9

Basic information

• Product Name: Benzoic acid, 2-butyl-
• Synonyms: butyl benzoic acid;2-(n-butyl)benzoic acid;2-n-butylbenzoic acid;2-(n-Butyl)-benzoesaeure;2-Butyl-benzoic acid;2-Butyl-benzoesaeure
• CAS NO: 54887-23-9
• Molecular Formula: C11H14O2
• Molecular Weight: 178.231
• Mol File: 54887-23-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 36-38 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 291.2±9.0 °C(Predicted)
• Density: 1.062±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoic acid, 2-butyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-butyl-(54887-23-9)
• EPA Substance Registry System: Benzoic acid, 2-butyl-(54887-23-9)

Safety Data

• Hazardous Substances Data: 54887-23-9(Hazardous Substances Data)

Usage

General Description

2-butyl benzoic acid is a derivative of benzoic acid, typically used as an intermediate or an additive in the pharmaceutical and chemical industry. It is often utilized in the synthesis of pharmaceuticals and other fine chemicals due to its unique chemical properties. 2-butyl benzoic acid is also used as a flavoring agent in food and beverage applications, as well as in the production of cosmetic and personal care products. This chemical is characterized by its aromatic and slightly fruity odor, and it is generally considered to be safe for use in these different sectors.

Upstream product

• 693-03-8 n-butyl magnesium bromide 
• 57598-33-1 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 19666-03-6 butyrophenone-o-carboxylic acid 
• 57629-47-7 2-(2-Butylphenyl)-4,4-dimethyl-2-oxazoline 
• 444343-55-9 butyltrifluoro-λ⁴-borane potassium salt 
• 65-85-0 benzoic acid 
• 88-67-5 2-Iodobenzoic acid 
• 42930-39-2 n-butylzinc chloride 
• 85-44-9 phthalic anhydride 
• 462-06-6 fluorobenzene 
• 89393-50-0 benzyne 
• 56635-66-6 N-methyl-N-(o-toluoyl)piperazine 
• 535-80-8 3-chlorobenzoate 
• 701923-86-6 3-Chloro-N-(2-hydroxy-1,1-dimethyl-ethyl)-benzamide 

Downstream Products

• 176088-71-4 (S)-N-(1-azabicyclo[2.2.2]oct-3-yl)-2-butylbenzamide 
• 72424-08-9 3-propyl-3H-isobenzofuran-1-one 
• 59137-63-2 (2-butyl-phenyl)-phenyl-methanone 
• 100256-40-4 2-(n-Butyl)-benzoesaeuremethylester 
• 54887-24-0 2-butylbenzoyl chloride 
• 34139-46-3 2-n-Butylphenyl-diazomethan 
• 59059-42-6 2-butylbenzaldehyde 
• 54887-25-1 2-Butyl-benzoic acid 2-diethylamino-ethyl ester 
• 85303-89-5 3-(2-Butyl-phenyl)-5-(3-methoxy-phenyl)-1H-[1,2,4]triazole 
• 85303-88-4 3-(2-Butyl-phenyl)-5-phenyl-1H-[1,2,4]triazole 
• 59636-02-1 o-(n-butyl)benzhydrazide 
• 177903-44-5 (2-Butyl-benzoyl)-phosphonic acid dimethyl ester 

Relevant articles and documents

Ligand-accelerated ortho -C-H alkylation of arylcarboxylic acids using alkyl boron reagents

A protocol for the Pd(II)-catalyzed ortho-C-H alkylation of phenylacetic and benzoic acids using alkylboron reagents is disclosed. Monoprotected amino acid ligands (MPAA) were found to significantly promote reactivity. Both potassium alkyltrifluoroborates and alkylboronic acids were compatible coupling partners. The possibility of a radical alkyl transfer to Pd(II) was also investigated.

Protoberberins from Reissert Compounds VI [1]. Diastereoselective Synthesis and Relative Configuration of 2-Benzoyl-1-cyano-1-(1-phenylalkyl)-1,2-dihydroisoquinolines

The alkylation of Reissert compounds 8 by sec-benzyl bromides 4, 7, and 10 diastereoselectively affords the title compounds 11 and 12. X-Ray structure analysis confirms an opposite configuration of the chiral centers in 11 and 12. The benzyl bromides 4, 7, and 10 are prepared by standard procedures.