54963-43-8

Basic information

• Product Name: Phenol, 4-chloro-3-methyl-, acetate
• CAS NO: 54963-43-8
• Molecular Formula: C9H9ClO2
• Molecular Weight: 184.622
• Mol File: 54963-43-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Phenol, 4-chloro-3-methyl-, acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-chloro-3-methyl-, acetate(54963-43-8)
• EPA Substance Registry System: Phenol, 4-chloro-3-methyl-, acetate(54963-43-8)

Safety Data

• Hazardous Substances Data: 54963-43-8(Hazardous Substances Data)

Usage

Description

Phenol, 4-chloro-3-methyl-, acetate, also known as 4-chloro-3-methylphenol acetate, is a chemical compound with the molecular formula C8H7ClO2. It is a derivative of phenol, characterized by the presence of a chlorine atom at the 4-position and a methyl group at the 3-position. Phenol, 4-chloro-3-methyl-, acetate is commonly used in various applications due to its unique chemical properties.

Uses

Used in Fragrance Industry:
Phenol, 4-chloro-3-methyl-, acetate is used as a fragrance ingredient for its distinctive scent. It is incorporated into the production of various consumer products, such as perfumes, colognes, and other scented items, to provide a pleasant and long-lasting aroma.
Used in Flavor Industry:
In the flavor industry, Phenol, 4-chloro-3-methyl-, acetate is used as a flavoring agent. It imparts a unique taste to food and beverage products, enhancing their overall flavor profile and consumer appeal.
Used in Pharmaceutical Industry:
Phenol, 4-chloro-3-methyl-, acetate is utilized in the synthesis of pharmaceuticals. Its chemical structure allows it to serve as a building block or intermediate in the production of various medicinal compounds, contributing to the development of new drugs and therapies.
Used in Agrochemical Industry:
Phenol, 4-chloro-3-methyl-, acetate is also employed in the agrochemical industry, where it is used in the synthesis of pesticides, herbicides, and other agricultural chemicals. Its unique properties make it a valuable component in the development of effective and targeted agrochemical products.
Used in Specialty Chemicals Industry:
Phenol, 4-chloro-3-methyl-, acetate is used in the production of specialty chemicals, which are tailored for specific applications in various industries. Its versatility and unique chemical properties make it a valuable component in the synthesis of these specialized compounds.
However, it is important to note that Phenol, 4-chloro-3-methyl-, acetate is considered to have low toxicity. Prolonged exposure or high concentrations of this chemical compound can have harmful effects on human health and the environment. Therefore, it is crucial to follow safe handling and proper disposal measures when working with Phenol, 4-chloro-3-methyl-, acetate to ensure the safety of both individuals and the environment.

Upstream product

• 59-50-7 4-Chloro-3-methylphenol 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 

Downstream Products

• 15968-57-7 4-chloro-3-methyl-2,6-dinitro-phenol 
• 7147-89-9 4-chloro-5-methyl-2-nitrophenol 
• 138212-12-1 4-chloro-3-(dichloromethyl)phenyl acetate 
• 165612-80-6 C₁₆H₁₂ClFO₂ 
• 1260667-96-6 (E)-1-(5-chloro-2-hydroxy-4-methylphenyl)-3-(4-fluorophenyl)prop-2-en-1-one 
• 1355198-80-9 2-hydroxy-5-chloro-4-methylacetophenone isonicotinoylhydrazone 
• 1214728-71-8 C₁₇H₂₄ClNO₅ 
• 63778-54-1 3-(bromomethyl)-4-chlorophenyl acetate 

Relevant articles and documents

Ultrasound-assisted synthesis and antimicrobial activity of tetrazole-based pyrazole and pyrimidine derivatives

New tetrazole-based pyrazole and pyrimidine derivatives were synthesized by an ultrasound irradiation method. All compounds were characterized by infrared spectroscopy (IR), 1H nuclear magnetic resonance (NMR), 13C NMR, mass spectrometry (MS) and elemental analysis and assessed in vitro for their efficacy as antimicrobial agents against four bacteria (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa) and two fungi (Candida albicans, Aspergillus Niger). Compounds 8a, 8e, 9a, 9b and 9e show potent activity against the tested strains compared to the reference drugs chloramphenicol and clotrimazole.

Synthesis, antimicrobial activity and anti-biofilm activity of novel tetrazole derivatives

In the development of antimicrobial agents, we designed and synthesized novel tetrazole derivatives. The structures of compounds 6a-f and 7a-f were characterized by IR, 1H NMR, 13C NMR, MS and elemental analysis. These compounds were tested for their antimicrobial activity against a series of strains Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa and for antifungal activity against the strains Candida albicans, Candida glabrata, and Candida tropicalis. Compounds 6e, 6f, 7a, and 7f exhibit potent antimicrobial activities compared to the reference drugs streptomycin and miconazole. Tetrazole derivatives 7a-f also inhibit biofilm formation and compound 7f exhibits best anti-biofilm activity with a biofilm inhibitory concentration (BIC) as low as 0.9 μm.

A new ferrocene-based bulky pyridine as an efficient reusable homogeneous catalyst

An effective approach to reusing a homogeneous catalyst has been demonstrated. A ferrocene-based bulky pyridine has been synthesized and utilized as a homogeneous catalyst for the synthesis of benzoylfumarates as well as for acetylation. After the reaction, the catalyst was separated by simple precipitation and reused without appreciable loss of activity. The Royal Society of Chemistry 2013.