54970-96-6

Basic information

• Product Name: 7-METHYL-2-(3-NITROPHENYL)IMIDAZO[1,2-A]PYRIDINE
• Synonyms: 7-METHYL-2-(3-NITROPHENYL)IMIDAZO[1,2-A]PYRIDINE;7-Methyl-2-(3-nitrophenyl)midazo[1,2-a]pyridine
• CAS NO: 54970-96-6
• Molecular Formula: C₁₄H₁₁N₃O₂
• Molecular Weight: 253.26
• Mol File: 54970-96-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 178-180°C
• Appearance: /
• Density: 1.31g/cm³
• Refractive Index: 1.67
• CAS DataBase Reference: 7-METHYL-2-(3-NITROPHENYL)IMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHYL-2-(3-NITROPHENYL)IMIDAZO[1,2-A]PYRIDINE(54970-96-6)
• EPA Substance Registry System: 7-METHYL-2-(3-NITROPHENYL)IMIDAZO[1,2-A]PYRIDINE(54970-96-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 54970-96-6(Hazardous Substances Data)

Usage

General Description

7-METHYL-2-(3-NITROPHENYL)IMIDAZO[1,2-A]PYRIDINE is a chemical compound that belongs to the imidazo[1,2-a]pyridine class of molecules. It is a yellow crystalline powder with a molecular formula C14H10N4O2 and a molecular weight of 266.25 g/mol. 7-METHYL-2-(3-NITROPHENYL)IMIDAZO[1,2-A]PYRIDINE is used in the field of medicinal chemistry, particularly in the development of potential pharmaceutical drugs. It has been studied for its potential biological activities, including its role as an inhibitor of certain enzymes and its potential use in the treatment of various diseases. The compound's structure and properties make it a subject of interest for researchers and scientists in the pharmaceutical and biomedical fields.

InChI:InChI=1/C14H11N3O2/c1-10-5-6-16-9-13(15-14(16)7-10)11-3-2-4-12(8-11)17(18)19/h2-9H,1H3

Upstream product

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Relevant articles and documents

Solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines by grindstone chemistry

The present work describes the solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines in excellent to nearly quantitative yields from 2-aminopyridines and a wide variety of ω-bromomethylketones using a grindstone procedure at 25°C to 30°C for 3 to

Iron(III)-catalyzed three-component domino strategy for the synthesis of imidazo[1,2-a]pyridines

An efficient, one-pot, three-component domino strategy has been demonstrated for the synthesis of imidazo[1,2-a]pyridines using a catalytic amount of Fe(III) chloride in high yields in air. A library of imidazo[1,2-a]pyridines was synthesized by the reaction of easily available aldehydes and 2-aminopyridines in a mixture of nitroalkane and DMF (2:1). This transformation presumably occurs by a sequential aza-Henry reaction/cyclization/denitration. The use of readily available chemicals as starting materials, inexpensive metal catalyst, aerobic reaction conditions, tolerance of a wide range of functional groups, and operational simplicity are the notable advantages of this present protocol.