55-94-7

Basic information

• Product Name: suxamethonium bromide
• Synonyms: suxamethonium bromide;Brevidil M;Myorelaxin;Suxamethonium dibromide
• CAS NO: 55-94-7
• Molecular Formula: 2Br*C₁₄H₃₀N₂O₄
• Molecular Weight: 450.207
• EINECS: 200-248-1
• Mol File: 55-94-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 225°
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: suxamethonium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: suxamethonium bromide(55-94-7)
• EPA Substance Registry System: suxamethonium bromide(55-94-7)

Safety Data

• RIDADR: 3249
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 55-94-7(Hazardous Substances Data)

Usage

Description

Suxamethonium bromide, also known as succinylcholine, is a neuromuscular blocking agent characterized by its ability to induce transient muscle relaxation during general anesthesia or to facilitate endotracheal intubation. It functions by mimicking the action of acetylcholine at the neuromuscular junction, leading to a brief period of muscle paralysis. This property is crucial for medical procedures that require controlled muscle relaxation. Its rapid metabolism by plasma cholinesterases ensures a short duration of action, typically 5-10 minutes, making it a preferred choice in certain clinical scenarios.

Uses

Used in Medical and Surgical Procedures:
Suxamethonium bromide is used as a muscle relaxant for facilitating [intubation or surgery] because of its ability to cause transient depolarization and paralysis of the skeletal muscles. This allows for the safe and effective intubation of patients or the performance of surgical procedures that require controlled muscle relaxation.
Used in Anesthesia:
In the field of anesthesia, suxamethonium bromide is used as an adjunct to general anesthesia for [inducing muscle relaxation] during surgical procedures. Its rapid onset and short duration of action make it suitable for situations where brief paralysis is required.
Used in Emergency Medicine:
Suxamethonium bromide is also used in emergency medicine as a rapid-sequence intubation agent, facilitating the safe and swift intubation of patients in critical conditions, such as those experiencing respiratory distress or requiring immediate airway protection.
Caution:
While suxamethonium bromide is effective for its intended uses, it is associated with potential side effects such as muscle pain, hyperkalemia, and malignant hyperthermia. Therefore, it is crucial to exercise caution in patients with certain medical conditions, including burns, neuromuscular diseases, or electrolyte imbalances, to mitigate the risk of adverse reactions.

InChI:InChI=1/C14H30N2O4.2BrH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

Upstream product

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