55009-88-6Relevant articles and documents
An improved procedure for the synthesis of perfluoroalkylacetylenes
Calleja-Rubio,Crette,Blancou
, p. 361 - 364 (2007/10/03)
A new and easy way to synthesize acetylene compounds is proposed. This synthesis is improved by including in one-pot, three reactions in a single step, with good yields. The reactants are commonly used compounds.
A general facile preparation of F-alkylacetylenes
Burton, Donald J.,Spawn, Terence D.
, p. 119 - 123 (2007/10/02)
F-Alkylethylenes can be exhaustively chlorinated under UV irradiation to give F-alkylpentachloroethanes in high yields. Subsequent dechlorination with three equivalents of zinc readily gives the F-alkylacetylenic zinc reagents, which on hydrolysis with aqueous HCl provide the corresponding F-alkylacetylenes in good yields. The methodology is applicable to F-alkyl groups of various chain lengths, and the F-acetylenic zinc reagent produced as the reaction intermediate can also be utilized in the direct preparation of functionalized F-alkylacetylenes.
EFFECTIVE DEPHOSPHORYLATION CATALYZED BY FLUORIDE ION: A NOVEL SYNTHESIS OF TERMINAL F-ALKYLACETYLENES FROM F-ALKANOYL CHLORIDES
Ishihara, Takashi,Maekawa, Takashige,Ando, Teiichi
, p. 1377 - 1378 (2007/10/02)
1H-F-1-Alkene-1-phosphonates, easily accessible from F-alkanoyl chlorides, underwent dephosphorylation on treatment with a catalytic amount of fluoride ion at 0 deg C to room temperature to give terminal F-alkylacetylenes in good yields.