55094-98-9

Basic information

• Product Name: Pentanedioic acid, 2-hydroxy-, dimethyl ester, (2R)-
• CAS NO: 55094-98-9
• Molecular Formula: C7H12O5
• Molecular Weight: 176.169
• Mol File: 55094-98-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Pentanedioic acid, 2-hydroxy-, dimethyl ester, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanedioic acid, 2-hydroxy-, dimethyl ester, (2R)-(55094-98-9)
• EPA Substance Registry System: Pentanedioic acid, 2-hydroxy-, dimethyl ester, (2R)-(55094-98-9)

Safety Data

• Hazardous Substances Data: 55094-98-9(Hazardous Substances Data)

Upstream product

• 13192-04-6 dimethyl 2-ketoglutarate 
• 328-50-7 α-ketoglutaric acid 

Downstream Products

• 2055536-64-4 (S)-3-(6-(3-(difluoromethoxy)-5-fluorophenyl)-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b] [1,4]oxazin-2-yl)-2,2-dimethylpropanoic acid 
• 138512-74-0 1-tert-butyl 2-methyl (2S,4R)-4-methylpyrrolidine-1,2-dicarboxylate 
• 145730-69-4 cis-L-4-methylproline methylester 

Relevant articles and documents

Biotechnological properties of sponges from northeast Brazil: Cliona varians as a Biocatalyst for Enantioselective Reduction of Carbonyl Compounds

To research the potential ability of whole marine sponges to act as biocatalysts, this paper describes for the first time the employment of whole Cliona varians sponge in the stereoselective reduction of prochiral α-keto esters and isatin to the corresponding chiral alcohols. The addition of D-fructose, D-glucose or sucrose remarkably increased the conversion ratios and stereoselectivities by this marine sponge. Furthermore, in the presence of D-glucose and D-maltose, the reduction of isatin by C. varians afforded the corresponding 3-hydroxyindolin-2-one with high conversions (85-90percent) and good enantioselectivities (60-74percent). These results showed that the marine sponge presents great potential to be used as biocatalyst for stereoselective reduction of carbonyl compounds.

Transfer hydrogenation of activated ketones using novel chiral Ru(II)-N-arenesulfonyl-1,2-diphenylethylenediamine complexes

A series of α-keto esters and α,α,α- trifluoromethyl ketones were reduced in high yields and excellent enantioselectivities under Ru-catalysed transfer hydrogenation using novel chiral N-arenesulfonyl-1,2-diphenylethylenediamine ligands.

NAD(P)+-NAD(P)H Models. 59. 1,2- Versus 1,4-Reduction of β,γ-Unsaturated α-Keto Ester

Depending on the reactivity of the reducing agent, β,γ-unsaturated α-keto ester is reduced into either β,γ-unsaturated α-hydroxy ester or saturated α-keto ester as the result of 1,2- or 1,4-reduction.