55136-97-5Relevant articles and documents
Rhenium-Catalyzed Dehydrogenative Coupling of Alcohols and Amines to Afford Nitrogen-Containing Aromatics and More
Mastalir, Matthias,Glatz, Mathias,Pittenauer, Ernst,Allmaier, Günter,Kirchner, Karl
supporting information, p. 1116 - 1120 (2019/05/16)
An efficient synthesis of quinolines, pyrimidines, quinoxalines, pyrroles, and aminomethylated aromatic compounds catalyzed by a well-defined Re(I) PNP pincer complex is described. All reactions proceed with liberation of dihydrogen and elimination of water. Under optimized reaction conditions a wide range of organic functional groups are tolerated. This study demonstrates that rhenium catalysts are performing extremely well in dehydrogenative processes with considerably lower catalyst loadings and shorter reaction times when compared to analogous Mn(I) complexes.
The activation of aminals and aminol ethers by sulfur dioxide and their reactions with electron rich aromatic compounds
Heaney, Harry,Papageorgiou, George,Wilkins, Robert F.
, p. 13361 - 13372 (2007/10/03)
Reactions of bis(dialkylamino)methanes and ethoxydialkylaminomethanes with nucleophilic aromatic heterocycles in the presence of sulfur dioxide result in the formation of the expected Mannich bases in good yields. Reactions of phenols are similarly activated by sulfur dioxide which lead to improved regioselectivity: in particular the reactions of 2,5-dimethylphenol result in the formation of 2-dialkylaminomethyl-3,6-dimethylphenol whereas reaction occurs at the I-position using the classical procedures.
