55244-03-6Relevant articles and documents
Formation of Thioamide Derivatives from Reactions of Isothiocyanates with Oxazol-2-amines
Crank, George,Khan, Humaid R.
, p. 447 - 458 (2007/10/02)
4-Substituted oxazol-2-amines react with isothiocyanates to give products having a thioamide function at C5.The reaction is considered to be an electrophilic process in competition with the usual reaction of the amino group with the isothiocyanate.The nature of the isothiocyanate and the type of substituent at C4 affect the amount of the thioamide product formed.Some chemical properties of the thioamides are also investigated.