55368-42-8Relevant articles and documents
Silver-catalyzed [3+2+1] annulation of aryl amidines with benzyl isocyanide
Lu, Xiaodong,Xin, Xiaoyi,Wan, Boshun
supporting information, p. 361 - 364 (2018/01/08)
A silver-catalyzed [3+2+1] annulation of amidines with benzyl isocyanide toward 2,4-diaryl-1,3,5-triazines was developed. A variety of symmetrical and unsymmetrical products were obtained in moderate to good yields. This work also features an oxidant-free approach to 2,4-disubstituted triazines.
A 2 - (4 - bromophenyl) -4 - biphenyl -6 - phenyl pyrimidine synthesis method (by machine translation)
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Paragraph 0010; 0039-0041, (2017/07/22)
The invention belongs to the technical field of organic electroluminescent material, discloses a 2 - (4 - bromophenyl) - 4 - biphenyl - 6 - phenyl pyrimidine synthesis method, the invention organic matter to bromophenylmethyl as raw materials, preparation
Synthesis and structure-activity relationship of 4-amino-2-phenylpyrimidine derivatives as a series of novel GPR119 agonists
Negoro, Kenji,Yonetoku, Yasuhiro,Maruyama, Tatsuya,Yoshida, Shigeru,Takeuchi, Makoto,Ohta, Mitsuaki
experimental part, p. 2369 - 2375 (2012/05/05)
Through preparation and examination of a series of novel 4-amino-2-phenylpyrimidine derivatives as agonists for GPR119, we identified 2-(4-bromophenyl)-6-methyl-N-[2-(1-oxidopyridin-3-yl)ethyl]pyrimidin-4-amine (9t). Compound 9t improved glucose tolerance in mice following oral administration and showed good pharmacokinetic profiles in rats.