5542-60-9Relevant articles and documents
The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions
Gabano, Elisabetta,Ravera, Mauro,Trivero, Francesca,Tinello, Stefano,Gallina, Andrea,Zanellato, Ilaria,Gariboldi, Marzia B.,Monti, Elena,Osella, Domenico
, p. 8268 - 8282 (2018)
Multi-action cisplatin-based mono- (1) and di-clofibric acid (2) Pt(iv) "combo" derivatives were synthesized via both traditional and microwave assisted procedures. The two complexes offered very good performances (IC50 values in a nanomolar ra
Diester compounds of PPAR protein activator
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, (2020/12/15)
The invention relates to diester compounds of a PPAR protein activator. The compounds are compounds shown in the formula (I) and pharmaceutically acceptable salts, prodrugs and solvates thereof, and apharmaceutical composition comprising the compounds and a synthesis method thereof. Furthermore, the invention relates to pharmaceutical composition comprising the compounds, and the pharmaceutical composition can be used for the prevention or treatment on diseases associated with PPPAR proteins.
Acetophenone compounds, preparation methods thereof and application thereof in regulating blood lipid
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Paragraph 0074; 0075; 0076, (2018/09/08)
The invention discloses a compound as shown in formula I or pharmaceutically acceptable salt and a preparation method thereof as well as application thereof in the preparation of drugs for regulatingblood lipid.