55542-27-3

Basic information

• Product Name: 17beta-hydroxy-17-(3-hydroxypropyl)androst-4-ene-4-one
• Synonyms: 17beta-hydroxy-17-(3-hydroxypropyl)androst-4-ene-4-one;17β-Hydroxy-17-(3-hydroxypropyl)androst-4-en-3-one
• CAS NO: 55542-27-3
• Molecular Formula: C₂₂H₃₄O₃
• Molecular Weight: 347.5115
• EINECS: 259-701-7
• Mol File: 55542-27-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Water Solubility: 61mg/L at 20℃
• CAS DataBase Reference: 17beta-hydroxy-17-(3-hydroxypropyl)androst-4-ene-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 17beta-hydroxy-17-(3-hydroxypropyl)androst-4-ene-4-one(55542-27-3)
• EPA Substance Registry System: 17beta-hydroxy-17-(3-hydroxypropyl)androst-4-ene-4-one(55542-27-3)

Safety Data

• Hazardous Substances Data: 55542-27-3(Hazardous Substances Data)

Usage

Type of compound

Synthetic anabolic steroid

Parent compound

Nandrolone

Properties

Strong androgenic and anabolic properties

Veterinary use

Promotes muscle growth and improves feed efficiency in livestock

Human use

Not approved due to potential for abuse and adverse effects

Mechanism of action

Binds to androgen receptors, leading to increased protein synthesis and muscle growth

Side effects

Acne, hair loss, increased risk of liver damage

Sports use

Prohibited due to potential performance-enhancing effects

Legal status

Classified as a controlled substance in many countries

Upstream product

• 53-43-0 dehydroepiandrosterone 
• 51480-24-1 tetrahydropyranyloxypropargylmagnesium bromide 
• 63-05-8 Androstenedione 
• 55542-26-2 17,23-dihydroxy-21,24-dinor-17βH-chol-4-en-20-yn-3-one 

Downstream Products

• 976-70-5 3-oxopregn-4-ene-21,17α-carbolactone 
• 976-71-6 canrenone 

Relevant articles and documents

ALDOSTERONE ANTAGONISTS.

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Having a method for the synthesis of intermediates spirondactone

The invention relates to a synthesis method of a chemical medicine, and concretely relates to a synthesis method of a spironolactone intermediate canrenone. The method comprises the following steps: carrying out an ethynylation reaction on a compound I 4-androstenedione (4AD), hydrogenating, carrying out an oxidation cyclization reaction, and carrying out a bromization and debromination reaction to obtain the compound V canrenone, and the above reaction route is shown in the specification. A synthesis method of the structure of an important 21,17-carboxy lactone spiro ring adopted in the invention is different from previous process modes, and is concise and efficient. The method has the characteristics of high yield, good selectivity, low cost, mild reactions, suitableness for industrialization, stability and easy realization.