55672-92-9 Usage
Description
Coenzyme A Sodium Salt, also known as CoA-SH, is a vital coenzyme involved in various biochemical reactions, including the synthesis and oxidation of fatty acids, as well as the production of energy in cells. It plays a crucial role in the transfer of acetyl groups and the activation of certain enzymes. Coenzyme A Sodium Salt is an essential component in the metabolic pathways of living organisms and has potential applications in various fields.
Uses
Used in Biochemical Research:
Coenzyme A Sodium Salt is used as a research tool for studying the role of Coenzyme A in various metabolic pathways, including glycerolipid biosynthesis in porcine adipose tissue and the synthesis of palmitoyl-CoA, which is required for palmitoylation and activation of proteins for regulated membrane fusion.
Used in Diagnostic Assays:
Coenzyme A Sodium Salt is used as a component in assays to measure the level of Alpha-methylacyl-CoA racemase (AMACR) in human blood samples using a nanoparticle electrochemical biosensor. This assay is important for the diagnosis and monitoring of certain diseases, such as cancer.
Used in Enzyme Assays:
Coenzyme A Sodium Salt is used in the chloramphenicol acetyltransferase (CAT) assay, which is a common method for detecting the activity of the CAT enzyme. This assay is useful for studying the regulation of gene expression and the activity of various enzymes.
Biochem/physiol Actions
Coenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes. In the presence of CoASH, organic carboxylic acids form acyl-CoA thioesters, which facilitates enzyme recognition. The acyl-CoA formed from xenobiotic carboxylic acids can add to the compound′s toxicity, which can lead to cellular metabolic dysfunction. It is involved in the oxidation of pyruvate in the Kreb′s cycle. CoA is needed for metabolic events. The bacterial CoA pathway is targeted for antimicrobial development. It mediates acyl group transfer and carbonyl activation. The CoA and its thioester levels are crucial for cellular homeostasis. CoA is also involved in regulating platelet aggregation and vasoconstriction. It acts as an essential cofactor in enzymatic acetyl transfer reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 55672-92-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,6,7 and 2 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 55672-92:
(7*5)+(6*5)+(5*6)+(4*7)+(3*2)+(2*9)+(1*2)=149
149 % 10 = 9
So 55672-92-9 is a valid CAS Registry Number.
InChI:InChI=1/C21H36N7O16P3S.Na/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35);/q;+1/t11-,14-,15-,16+,20?;/m1./s1
