55695-51-7

Basic information

• Product Name: (4-CHLOROPHENYL)(4-PIPERIDYL)METHANONE HYDROCHLORIDE
• Synonyms: (4-CHLOROPHENYL)-4-PIPERIDINYL-METHANONE, HYDROCHLORIDE;(4-CHLOROPHENYL)(4-PIPERIDYL)METHANONE HYDROCHLORIDE;(4-CHLORO-PHENYL)-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE;4-(P-CHLOROBENZOYL)PIPERIDINE HYDROCHLORIDE;4-(4-CHLOROBENZOYL)PIPERIDINE HCL;4-(4-CHLOROBENZOYL)-PIPERIDINE HYDROCHLORIDE;BUTTPARK 99\50-18;(4-Chlorophenyl)-4-piperidinylmethanoneHCl
• CAS NO: 55695-51-7
• Molecular Formula: C₁₂H₁₄ClNO*ClH
• Molecular Weight: 260.16
• Product Categories: Aromatics
• Mol File: 55695-51-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 238-239°C
• Boiling Point: 356.2 °C at 760 mmHg
• Flash Point: 169.2 °C
• Appearance: /
• Vapor Pressure: 2.96E-05mmHg at 25°C
• Storage Temp.: -20°C Freezer
• Solubility: Methanol, Water
• CAS DataBase Reference: (4-CHLOROPHENYL)(4-PIPERIDYL)METHANONE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-CHLOROPHENYL)(4-PIPERIDYL)METHANONE HYDROCHLORIDE(55695-51-7)
• EPA Substance Registry System: (4-CHLOROPHENYL)(4-PIPERIDYL)METHANONE HYDROCHLORIDE(55695-51-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 55695-51-7(Hazardous Substances Data)

Usage

Description

(4-Chlorophenyl)(4-piperidyl)methanone hydrochloride, with the chemical abstracts service number 55695-51-7, is a synthetic compound that plays a significant role in the field of organic synthesis. It is characterized by its unique molecular structure, which consists of a 4-chlorophenyl group and a 4-piperidinyl group connected through a methanone bridge. (4-CHLOROPHENYL)(4-PIPERIDYL)METHANONE HYDROCHLORIDE is known for its potential applications in various chemical processes and industries.

Uses

Used in Organic Synthesis:
(4-Chlorophenyl)(4-piperidyl)methanone hydrochloride is used as a key intermediate in organic synthesis for the development of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure allows it to serve as a building block or a precursor in the synthesis of complex organic molecules, contributing to the advancement of chemical research and product development.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4-chlorophenyl)(4-piperidyl)methanone hydrochloride is utilized as a starting material or a synthetic intermediate for the production of various drug candidates. Its presence in the molecular structure of these drug candidates can potentially influence their pharmacological properties, such as potency, selectivity, and bioavailability, making it an essential component in drug discovery and development processes.
Used in Agrochemical Industry:
(4-Chlorophenyl)(4-piperidyl)methanone hydrochloride also finds applications in the agrochemical industry, where it is employed as a component in the synthesis of various agrochemical products, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, thereby contributing to improved crop yields and agricultural productivity.

InChI:InChI=1/C12H14ClNO.ClH/c13-11-3-1-9(2-4-11)12(15)10-5-7-14-8-6-10;/h1-4,10,14H,5-8H2;1H

Upstream product

• 498-94-2 isonipecotic acid 
• 637-87-6 1-Chloro-4-iodobenzene 
• 139290-70-3 tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 209808-06-0 tert-butyl 4-(4-chlorobenzoyl)piperidine-1-carboxylate 

Downstream Products

• 209808-06-0 tert-butyl 4-(4-chlorobenzoyl)piperidine-1-carboxylate 
• 209807-41-0 N,N-Diethyl-4-(4-chlorophenyl-piperidin-4-ylidene-methyl)-benzamide 
• 209808-08-2 4-(α-hydroxy-α-(4-N-tert-butoxycarbonylpiperidinyl)-4-chlororobenzyl)-N,N-diethylbenzamide 
• 654673-72-0 (thien-2-yl)-[4-(4-chlorobenzoyl)piperidin-1-ylmethyl]-ketone 
• 389890-69-1 (E)-3-(5-Bromo-2-methoxy-phenyl)-N-{2-[4-(4-chloro-benzoyl)-piperidin-1-yl]-ethyl}-acrylamide 
• 353522-09-5 [4-(4-Chlorobenzoyl)-piperidin-1-yl]-(1H-indol-5-yl)-methanone 
• 298699-05-5 [1-(2-Aminoethyl)-4-piperidinyl](4chlorophenyl)methanone trifluoroacetate 
• 885595-17-5 4-(4-chlorobenzoyl)piperidine-1-carboxylic acid benzyl ester 
• 416849-59-7 C₂₃H₂₇ClN₄O₂ 
• 1223425-52-2 3-{4-[4-(4-chlorobenzoyl)piperidine-1-carbonyl]phenyl}oxazolidin-2-one 
• 1223431-66-0 (6-bromopyridin-3-yl)[4-(4-chlorobenzoyl)piperidin-1-y1]methanone 
• 1223431-03-5 (R)-3-{4-[4-(4-chlorobenzoyl)piperidine-1-carbonyl]phenyl}-4-isopropyloxazolidin-2-one 
• 1352010-97-9 2,2,2-trifluoro-1-(trifluoromethyl)ethyl 4-(4-chlorobenzoyl)piperidine-1-carboxylate 

Relevant articles and documents

MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS

The invention provides compounds of formula (I) or pharmaceutically acceptable salt thereof wherein ring A represents group A-I, A-II or A-III. Al represents -C(R4a)(R4a)-, -C(R4a)= -N(R4b)-, -N= -O- or -S-; A2 represents -C(R4c)(R4c)-, -C(R4c)= or -0-; A3 represents -C(R4c)(R4c)-, -C(R4c)= or -0-; A4 represents -C(R4a)(R4a)-, -C(R4a)= -N= -O- or -S-; A5 represents -C(R4a)(R4a)-, -C(R4a)= -N(R4b)-, -N= -O- or -S-; A6 represents -C(R4c)(R4c)- or -C(R4c)=; A7 represents -C(R4a)(R4a)-, -C(R4a)= -N= -O- or -S-; A8 represents -C(R4a)(R4a)-, -N(R4b)-, -O- or -S-; A9 represents -C(R4c)(R4c)- or -0-; A10 represents -C(R4c)(R4c)- or -0-; A11 represents -C(R4c)(R4c)- or -0-; A12 represents -C(R4a)(R4a)-, -O- or -S-; wherein group A-I, group A-II and group A-III de not contain adjacent oxygen atoms, adjacent oxygen and sulfur atoms or adjacent oxygen and nitrogen atoms or a moiety selected from the group consisting of N-C-N, N-C-S, S-C-S, O-C-N, O-C-O and O-C-S, wherein in each case the carbon atom in the N-C-N, N-C-S, S-C-S, O-C-N, O-C-O and O-C-S moiety is saturated; B1, B2, B3 and B4 represent independently C(R3) or N, wherein no more than two of B1, B2, B3 and B4 represent N; n is 1 or 2; and R1, R2, R3, R4a, R4b and R4c are as defined in the claims, as well as methods of using the compounds to treat proliferation diseases, in particular cancer.

Benzoylpiperidylalkylindoles

New benzoylpiperidylalkylindoles and related compounds possessing tranquilizing, anti-hypertensive and analgesic properties and a process for the preparation thereof are described.