55737-66-1

Basic information

• Product Name: 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID
• Synonyms: 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID;RARECHEM AL BE 0920;2-Nitroterephthalic acid 4-methyl ester, 97%;4-methoxycarbonyl-2-nitrobenzoic acid
• CAS NO: 55737-66-1
• Molecular Formula: C₉H₇NO₆
• Molecular Weight: 225.15
• Mol File: 55737-66-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 133-135°C
• Boiling Point: 393.5°C at 760 mmHg
• Flash Point: 191.8°C
• Appearance: /
• Density: 1.486g/cm³
• Vapor Pressure: 6.71E-07mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Insoluble in water.
• CAS DataBase Reference: 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID(55737-66-1)
• EPA Substance Registry System: 2-NITRO-4-METHOXYCARBONYL BENZOIC ACID(55737-66-1)

Safety Data

• Hazardous Substances Data: 55737-66-1(Hazardous Substances Data)

Usage

General Description

2-Nitro-4-Methoxycarbonyl Benzoic Acid is a chemical compound that belongs to the class of organic compounds known as benzoic acids, which are compounds containing a benzoic acid or its derivative. Structurally, it is characterized by the presence of a benzene ring attached to a carboxylic acid group, a nitro functional group at its second position, and a methoxycarbonyl group at its fourth position. Due to its specific functional groups, this compound exhibits unique chemical properties and reactivities. It is typically used in various chemical reactions and processes, including organic synthesis, as a precursor or an intermediate compound. Additionally, like other types of benzoic acid derivatives, it also has potential applications in pharmaceuticals and other allied fields.

InChI:InChI=1/C9H7NO6/c1-5(11)16-6-2-3-7(9(12)13)8(4-6)10(14)15/h2-4H,1H3,(H,12,13)

Upstream product

• 67-56-1 methanol 
• 610-29-7 2-nitroterephthalic acid 

Downstream Products

• 85743-02-8 2-amino-benzene-1,4-dicarboxylic acid,4-methyl ester 
• 860708-99-2 N-methyl-3-nitro-N-phenyl-terephthalamic acid methyl ester 
• 167903-04-0 3-amino-4-(methylamino)carbonylbenzoic acid 
• 183431-11-0 methyl 3-amino-4-(methylamino)carbonylbenzoate 
• 183431-09-6 methyl 4-(methylamino)carbonyl-3-nitrobenzoate 
• 180132-98-3 2-(2-nitro-4-methoxycarbonylbenzoylamino)benzoic acid 1-hexyl ester 
• 180132-99-4 2-(2-amino-4-methoxycarbonylbenzoylamino)benzoic acid 1-hexyl ester 
• 180133-09-9 2-[2-(2-aminobenzoylamino)-4-methoxycarbonylbenzoylamino]benzoic acid 1-hexyl ester 
• 182301-30-0 2-[2-(2-nitrobenzoylamino)-4-methoxycarbonylbenzoylamino]benzoic acid 1-hexyl ester 
• 180133-15-7 2-(2-Amino-4-methoxycarbonyl-benzoylamino)-terephthalic acid bis-(1-isobutyl-3-methyl-butyl) ester 
• 180133-14-6 2-(4-Methoxycarbonyl-2-nitro-benzoylamino)-terephthalic acid bis-(1-isobutyl-3-methyl-butyl) ester 
• 180133-11-3 2-{2-[2-(2-amino-4-methoxycarbonylbenzoylamino)benzoylamino]-4-methoxycarbonylbenzoylamino}benzoic acid 1-hexyl ester 
• 180133-10-2 2-{2-[2-(2-nitro-4-methoxycarbonylbenzoylamino)benzoylamino]-4-methoxycarbonylbenzoylamino}benzoic acid 1-hexyl ester 
• 180133-01-1 2-{2-[2-(2-hexanoylamino-4-hydroxycarbonylbenzoylamino)benzoylamino]-4-hydroxycarbonylbenzoylamino}benzoic acid 1-hexyl ester 

Relevant articles and documents

NEUROTRYPSIN INHIBITORS

The invention relates to acylamino-phthalic acid amides and related compounds of formula (I) wherein A is -CONR3R4,-NR5COR6, -NHR7, -OR8, -mR9, -CH2NRI0R11, -(CH2)2-R12, -CH=CH-R12, -C=C-R12, optionally substituted phenyl, optionally substituted thiophenyl, or optionally substituted 1,2,3-triazol-4-yl, W is hydrogen, hydroxy or carboxymethoxy, Y is carboxy, methoxycarbonyl or 2H-tetrazol-5-yl, and the various substituents R have the meanings indicated in the description. These compounds are useful for the treatment and/or prophylaxis of skeletal muscle atrophy, schizophrenia and Alzheimer?s disease, and as cognitive enhancers.

Substituted benzene derivatives useful as neuraminidase inhibitors

A compound of the Formula (I): STR1 or pharmaceutically-suitable salts or prodrug forms thereof, wherein: n is 0-1; m is 0; p is 0-1; R1 is --CO2 H; R2 is selected from the group consisting of H, --OH, and --NH2 ; R3 is H; R4 is --C(O)NHR8 ; R5 is --NHC(R6)NH2 R6 is selected from the group consisting of =NH, =NOH, =NCN, =O, and =S; and R8 is selected from the group consisting of C1 -C4 linear or branched alkyl substituted with 0-3 halogens on each carbon.

Oligoanthranilamides. Non-peptide subunits that show formation of specific secondary structure

A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. 1H NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.