5581-55-5 Usage
Description
METHYL-D3-AMINE, also known as M285560, is a deuterated isotope of Methylamine. It is a common chemical reagent with unique properties due to the presence of deuterium, a stable isotope of hydrogen. This characteristic makes it valuable in various applications, particularly in the field of chemical synthesis and research.
Uses
Used in Pharmaceutical Synthesis:
METHYL-D3-AMINE is used as a chemical reagent for the synthesis of 2-aminoquinolines. These compounds are potent and selective inhibitors of neuronal nitric oxide synthase, which plays a crucial role in neurodegenerative disorders. By incorporating METHYL-D3-AMINE into the synthesis process, researchers can develop more effective treatments for conditions such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis.
Used in Research and Development:
In the field of research and development, METHYL-D3-AMINE is utilized as a valuable tool for studying the effects of deuterium on chemical reactions and molecular interactions. The presence of deuterium in METHYL-D3-AMINE can provide insights into reaction mechanisms, kinetics, and the behavior of molecules in various environments. This information can be crucial for the development of new drugs, materials, and technologies.
Used in Isotope Labeling:
METHYL-D3-AMINE can also be employed in isotope labeling techniques, which involve the substitution of hydrogen atoms with deuterium. This method is widely used in various scientific disciplines, including biochemistry, pharmacology, and materials science, to study the structure, dynamics, and interactions of molecules. By using METHYL-D3-AMINE as a labeling agent, researchers can gain a deeper understanding of molecular processes and develop more targeted and effective therapies for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5581-55-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,8 and 1 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5581-55:
(6*5)+(5*5)+(4*8)+(3*1)+(2*5)+(1*5)=105
105 % 10 = 5
So 5581-55-5 is a valid CAS Registry Number.
InChI:InChI=1/CH5N/c1-2/h2H2,1H3/i1D3
5581-55-5Relevant articles and documents
β-deuterium Isotope Effects on Amine Basicity, Inductive and Stereochemical
Perrin, Charles L.,Ohta, Brian K.,Kuperman, Joshua
, p. 15008 - 15009 (2007/10/03)
Secondary β deuterium isotope effects on acidity constants of ammonium ions are measured using a remarkably precise NMR titration method. Deuteration is found to increase the basicity of methylamine, dimethylamine, benzylamine, and N,N-dimethylaniline. The effect is attributed to a lowered zero-point energy of a CH bond adjacent to an amine nitrogen. The method permits a determination of the stereochemical dependence of the isotope effect in a locked piperidine, and it is found that deuteration is more effective when antiperiplanar to a lone pair. The values are consistent with a cos2 dependence on dihedral angle, with no detectable angle-independent inductive effect. Copyright
