5585-85-3 Usage
Description
(17beta)-17-hydroxy-17-methylandrosta-4,6-dien-3-one, also known as methyldrostanolone or methyldienone, is a synthetic anabolic steroid derived from testosterone. It is characterized by its ability to bind to the androgen receptor and stimulate the growth of skeletal muscle tissue, making it a potent agent for increasing muscle mass and strength.
Used in Bodybuilding and Athletic Performance Enhancement:
(17beta)-17-hydroxy-17-methylandrosta-4,6-dien-3-one is used as a performance-enhancing drug for increasing muscle mass and strength in bodybuilding and athletic performance. Its anabolic effects are attributed to its ability to bind to the androgen receptor, promoting the growth of skeletal muscle tissue.
However, it is important to note that the use of this chemical carries significant risks and side effects, including liver damage, cardiovascular issues, and potential for abuse. Due to its potential for misuse and harmful health effects, the use of (17beta)-17-hydroxy-17-methylandrosta-4,6-dien-3-one is regulated in many countries.
Check Digit Verification of cas no
The CAS Registry Mumber 5585-85-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,8 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5585-85:
(6*5)+(5*5)+(4*8)+(3*5)+(2*8)+(1*5)=123
123 % 10 = 3
So 5585-85-3 is a valid CAS Registry Number.
5585-85-3Relevant articles and documents
Natural Product Diversification by One-Step Biocatalysis using Human P450 3A4
Fessner, Nico D.,Grimm, Christopher,Srdi?, Matic,Weber, Hansj?rg,Kroutil, Wolfgang,Schwaneberg, Ulrich,Glieder, Anton
, (2021/12/03)
Efficient synthetic techniques for the diversification of natural products are incremental for drug discovery processes of the pharmaceutical industry because these complex bioactive compounds often require an adjustment of properties. Human liver P450 3A4, key player of the body's detoxification system and decisive factor of a drug's metabolic fate, is renowned for its broad substrate scope including many natural products. In this study, we investigated the synthetic potential of human P450 3A4 for the diversification of natural product classes and isolated the produced metabolites of six selected natural products at a preparative 100-mg scale. Aided by efficient expression levels in P. pastoris, this whole-cell biocatalyst was found to be highly effective at the intended job allowing the identification of a total of 31 authentic human metabolites, many of them for the first time. By revealing an unprecedented degree of diversification, this study extends the synthetic repertoire for efficient enzymatic natural product modification in a one-step fashion and adds a completely new view to an old enzyme traditionally used for inhibition and toxicology studies.