55873-09-1

Basic information

• Product Name: 4(1H)-Pyrimidinone, 2-chloro- (9CI)
• Synonyms: 4(1H)-Pyrimidinone, 2-chloro- (9CI);2-Chloropyrimidin-4-ol;4(3H)-PyriMidinone, 2-chloro-;2-chloropyrimidin-4(1H)-one;2-chloro-1,4-dihydropyrimidin-4-one;2-Chloro-4(3H)-pyrimidinone;2-Chloropyrimidin-4(3H)-one
• CAS NO: 55873-09-1
• Molecular Formula: C4H3ClN2O
• Molecular Weight: 130.53242
• Product Categories: PYRIMIDINE
• Mol File: 55873-09-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 328.1 °C at 760 mmHg
• Flash Point: 152.3 °C
• Appearance: /
• Density: 1.55 g/cm³
• Vapor Pressure: 0.000101mmHg at 25°C
• Refractive Index: 1.632
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 6.37±0.40(Predicted)
• CAS DataBase Reference: 4(1H)-Pyrimidinone, 2-chloro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 2-chloro- (9CI)(55873-09-1)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 2-chloro- (9CI)(55873-09-1)

Safety Data

• Hazardous Substances Data: 55873-09-1(Hazardous Substances Data)

Usage

Description

4(1H)-Pyrimidinone, 2-chloro(9CI) is an organic compound with the molecular formula C4H3ClN2O. It is a derivative of pyrimidine, a heterocyclic aromatic organic compound that is an important component in the structure of nucleic acids. The 2-chloro substitution in this compound provides unique chemical properties and reactivity, making it a valuable intermediate in the synthesis of various pharmaceutical compounds.

Uses

Used in Pharmaceutical Industry:
4(1H)-Pyrimidinone, 2-chloro(9CI) is used as a key intermediate in the synthesis of pyrazole derivatives, which are known for their antitumor properties. These pyrazole derivatives have the potential to be developed into effective drugs for the treatment of various types of cancer.
4(1H)-Pyrimidinone, 2-chloro(9CI)'s reactivity and structural features make it a versatile building block for the development of novel anticancer agents. By incorporating 4(1H)-Pyrimidinone, 2-chloro(9CI) into the molecular structure of pyrazole derivatives, researchers can explore new avenues for designing drugs with improved efficacy, selectivity, and reduced side effects.

InChI:InChI=1/C4H3ClN2O/c5-4-6-2-1-3(8)7-4/h1-2H,(H,6,7,8)

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