55934-22-0

Basic information

• Product Name: 2,4-DICHLORO-7-METHOXY QUINOLINE
• Synonyms: 2,4-DICHLORO-7-METHOXY QUINOLINE
• CAS NO: 55934-22-0
• Molecular Formula: C₁₀H₇Cl₂NO
• Molecular Weight: 228.077
• Mol File: 55934-22-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 132-133 °C(Solv: ethanol (64-17-5))
• Boiling Point: 327.9 °C at 760 mmHg
• Flash Point: 152.1 °C
• Appearance: /
• Density: 1.384 g/cm³
• Vapor Pressure: 0.000374mmHg at 25°C
• Refractive Index: 1.63
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.79±0.50(Predicted)
• CAS DataBase Reference: 2,4-DICHLORO-7-METHOXY QUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DICHLORO-7-METHOXY QUINOLINE(55934-22-0)
• EPA Substance Registry System: 2,4-DICHLORO-7-METHOXY QUINOLINE(55934-22-0)

Safety Data

• Hazardous Substances Data: 55934-22-0(Hazardous Substances Data)

Usage

General Description

2,4-Dichloro-7-methoxy quinoline is a chemical compound with the molecular formula C10H7Cl2NO. It is a member of the quinoline family of compounds and is characterized by its two chlorine atoms and a methoxy group attached to the quinoline ring. This chemical has been used in the production of several pharmaceuticals, agrochemicals, and organic materials due to its structural diversity and unique chemical properties. It is known for its role as an intermediate in the synthesis of various drugs and has also been investigated for its potential biological activities. Additionally, 2,4-Dichloro-7-methoxy quinoline is used as a building block in chemical research and has shown promise in the development of new compounds with a range of potential applications.

InChI:InChI=1/C10H7Cl2NO/c1-14-6-2-3-7-8(11)5-10(12)13-9(7)4-6/h2-5H,1H3

Upstream product

• 99074-22-3 4-chloro-7-methoxy-quinolin-2-ol 
• 141-82-2 malonic acid 
• 536-90-3 m-Anisidine 
• 99071-95-1 2-amino-7-methoxy-quinolin-4-ol 
• 68050-20-4 4-chloro-7-methoxy-quinolin-2-ylamine 
• 27037-34-9 4-hydroxy-7-methoxy-2-oxo-1,2-dihydroquinoline 
• 855765-21-8 4-hydroxy-5-methoxyquinoline-2(1H)-one 

Downstream Products

• 1409964-05-1 4-chloro-2-(4-isopropoxyphenyl)-7-methoxyquinoline 

Relevant articles and documents

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Syntheses and fluorescent properties of 6-methoxy-2-oxoquinoline-3,4- dicarbonitriles and 6,7-dimethoxy-2-oxoquinoline-3,4-dicarbonitriles

4-Chlorocarbostyrils 3, 12, 17, 24, 26 with methoxy substituents in 6, 7, or 6,7-position react with potassium cyanide in a p-toluenesulfinate mediated reaction either to the highly fluorescent and stable 2-oxoquinoline-3,4- dicarbonitriles 6, 27, 29, 30 or at slightly lower temperatures to 4-monocarbonitriles 5, 13, 18. 4-Chlorocarbostyril 3 and lithium p-toluenesulfinate gave pure 4-toluenesulfonylquinolone 4, which reacted with potassium cyanide either to monocarbonitrile 5 or dicarbonitrile 6, depending on the reaction conditions. 4-Trifluoromethylquinolones 9 and 19 were prepared for fluorescence comparison from the appropriate methoxyaniline and 4,4,4-trifluoroacetoacetate. The fluorescence properties such as emission wavelengths and quantum yields of 6-methoxyderivatives 4, 5, 6, 9, 13 were studied and compared with those of 7-methoxy derivatives 18, 19 and 6,7-dimethoxyderivatives 27, 28, 29, 30. 6,7-Dimethoxy derivatives show best results, showing long-waved fluorescence spectra up to 520 nm and acceptable quantum yields up to 0.46 for 3,4-dicyano derivative 27 excited at 440 nm in acetonitrile.

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