56015-84-0

Basic information

• Product Name: Urea, N,N-diethyl-N''''-(4-Methoxyphenyl)-
• Synonyms: Urea, N,N-diethyl-N''''-(4-Methoxyphenyl)-;1,1-DIETHYL-3-(4-METHOXYPHENYL)UREA
• CAS NO: 56015-84-0
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.28352
• Mol File: 56015-84-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 391.6°Cat760mmHg
• Flash Point: 190.6°C
• Appearance: /
• Density: 1.093g/cm³
• Vapor Pressure: 2.43E-06mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: Urea, N,N-diethyl-N''''-(4-Methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N,N-diethyl-N''''-(4-Methoxyphenyl)-(56015-84-0)
• EPA Substance Registry System: Urea, N,N-diethyl-N''''-(4-Methoxyphenyl)-(56015-84-0)

Safety Data

• Hazardous Substances Data: 56015-84-0(Hazardous Substances Data)

Usage

General Description

Urea, N,N-diethyl-N''-(4-methoxyphenyl)- is a chemical compound with the molecular formula C13H20N2O2. It is a derivative of urea and is often used as a reagent in organic chemistry. Urea, N,N-diethyl-N''''-(4-Methoxyphenyl)- is commonly utilized as a reactant in the synthesis of various pharmaceuticals and agrochemicals due to its versatile nature and ability to facilitate the formation of carbon-carbon and carbon-heteroatom bonds. Additionally, it is also employed in the production of dyes and pigments, as well as in the manufacturing of polymers and other industrial materials. Overall, urea, N,N-diethyl-N''-(4-methoxyphenyl)- is a crucial component in numerous chemical processes and has diverse applications across various industries.

InChI:InChI=1/C12H18N2O2/c1-4-14(5-2)12(15)13-10-6-8-11(16-3)9-7-10/h6-9H,4-5H2,1-3H3,(H,13,15)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 88-10-8 N,N-diethylcarbamyl chloride 
• 5416-93-3 4-Methoxyphenyl isocyanate 
• 109-89-7 diethylamine 
• 201230-82-2 carbon monoxide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 3532-17-0 4-methoxybenzoyl azide 

Downstream Products

• 105363-74-4 C₂₄H₃₄N₄O₃ 
• 15932-18-0 N,N-Diethyl-N'-(4-methoxy-phenyl)-chlorameisensaeure-amidin 

Relevant articles and documents

Direct conversion of carboxylic acids to various nitrogen-containing compounds in the one-pot exploiting curtius rearrangement

Herein we report, a single-pot multistep conversion of inactivated carboxylic acids to various N-containing compounds using a common synthetic methodology. The developed methodology rendered the use of carboxylic acids as a direct surrogate of primary amines, for the synthesis of primary ureas, secondary/tertiary ureas, O/S-carbamates, benzoyl ureas, amides, and N-formyls, exploiting the Curtius reaction. This approach has a potential to provide a diversified library of N-containing compounds, starting from a single carboxylic acid, based on the selection of the nucleophile.

Synthesis of unsymmetrical ureas by sulfur-assisted carbonylation with carbon monoxide and oxidation with molecular oxygen under mild conditions

With ambient pressure of carbon monoxide and oxygen at room temperature, N,N-dialkyl-N′-arylureas were selectively accessible from secondary amines, aromatic amines, and sulfur in good to excellent yields. For example, N-butyl-N-methyl-N′-(3,4-dichlorophenyl)urea, which is used as a herbicide (neburon), was afforded successfully from butylmethylamine (2 equiv), 3,4-dichloroaniline (1 equiv) and sulfur (1 equiv) in 79% (21.8 g) yield using carbon monoxide (0.1 MPa) and oxygen (0.1 MPa) at 20°C in DMF. Georg Thieme Verlag Stuttgart.

Synthesis of 2,4-diaminoquinazoline derivatives

A series of 6- and 7-substituted derivatives of 2-(N,N-diethylamino)-4-(N,N-dimethylamino)quinazoline have been synthesized. The synthesis consists in converting N-phenyl-N',N'-diethylurea into chloroamidines which are treated with N,N-dimethylcyanamide t