5625-52-5

Basic information

• Product Name: 1 - Methylpiperazine - 2,5 - dione
• Synonyms: 1 - Methylpiperazine - 2,5 - dione;1-methyl-2,5-Piperazinedione
• CAS NO: 5625-52-5
• Molecular Formula: C₅H₈N₂O₂
• Molecular Weight: 128.12922
• Mol File: 5625-52-5.mol
• Article Data: 12

Chemical Properties

• Melting Point: 141-143 °C
• Boiling Point: 427°Cat760mmHg
• Flash Point: 212.1°C
• Appearance: /
• Density: 1.202g/cm³
• Vapor Pressure: 1.69E-07mmHg at 25°C
• Refractive Index: 1.481
• PKA: 13.04±0.20(Predicted)
• CAS DataBase Reference: 1 - Methylpiperazine - 2,5 - dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1 - Methylpiperazine - 2,5 - dione(5625-52-5)
• EPA Substance Registry System: 1 - Methylpiperazine - 2,5 - dione(5625-52-5)

Safety Data

• Hazardous Substances Data: 5625-52-5(Hazardous Substances Data)

Usage

General Description

1-Methylpiperazine-2,5-dione, also known as N-Methylpiperazinedione, is a chemical compound with the molecular formula C6H10N2O2. It is a white crystalline solid that is soluble in water and ethanol. 1 - Methylpiperazine - 2,5 - dione is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also utilized as a building block for the production of various organic compounds. Furthermore, 1-Methylpiperazine-2,5-dione has potential applications in the field of medicinal chemistry for the development of new drugs. Overall, this chemical serves multiple industrial and scientific purposes due to its versatile reactivity and stability.

InChI:InChI=1/C5H8N2O2/c1-7-3-4(8)6-2-5(7)9/h2-3H2,1H3,(H,6,8)

Upstream product

• 29816-01-1 Glycylsarcosine 
• 38082-72-3 sarcosine-glycine 
• 24515-53-5 [(2-chloroacetyl)(methyl)amino]acetic acid ethyl ester 
• 5076-82-4 sarcosine anhydride 
• 174311-10-5 methyl N'-(tert-butoxycarbonyl)glycylsarcosinate 
• 145590-97-2 N-tert-butoxycarbonylglycylsarcosine ethyl ester 
• 65332-01-6 methyl N-(2-chloroacetyl)glycine 

Downstream Products

• 109-01-3 1-methyl-piperazine 
• 59136-05-9 1-benzyl-4-methylpiperazine-2,5-dione 
• 79247-68-0 1-Methoxymethyl-4-methyl-piperazine-2,5-dione 
• 170376-79-1 1-Acetyl-4-methylpiperazine-2,5-dione 
• 562814-60-2 3,6-dihydro-1-methyl-5-methylthiopyrazin-2(1H)-one 
• 562814-58-8 1-methylpiperazin-2,5-dithione 
• 562814-59-9 1-methyl-5-thioxopiperazin-2-one 
• 562814-61-3 1-methyl-5-cyanoiminopiperazin-2-one 
• 155090-89-4 1-benzyl-3,6-dibromo-4-methylpiperazine-2,5-dione 
• 67-99-2 dl-Gliotoxin 
• 1668-07-1 dl-dehydrogliotoxin 
• 79247-63-5 (1R,5R)-6-(2-Hydroxymethyl-6-methoxy-phenyl)-3-(4-methoxy-phenyl)-8-methyl-2,4-dithia-6,8-diaza-bicyclo[3.2.2]nonane-7,9-dione 
• 565433-79-6 2-(2,5-Bis-acetylsulfanyl-4-methyl-3,6-dioxo-piperazin-1-yl)-3-methoxy-benzoic acid methyl ester 

Relevant articles and documents

N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE

The invention relates to compounds of formula (I), or a salt thereof wherein R1, A, L, and R2 and n are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are ανβ1 integrin inhibitors that are useful for treating tissue specific fibrosis.

Solvent-free, efficient synthesis of 2,5-piperazinediones from Boc-protected dipeptide esters under microwave irradiation

Microwave irradiation allows the efficient, solvent-free transformation of N-Boc dipeptide esters into 2,5-piperazinediones. The microwave-assisted conditions were found to be much better than traditional heating in terms of reaction time, yield and stere

Isotopically enriched N-substituted piperazines and methods for the preparation thereof

In some embodiments, this invention pertains to isotopically enriched N-substituted piperazines. In some embodiments, this invention pertains to methods for the preparation of isotopically enriched N-substituted piperazines.